Current Organic Chemistry - Volume 19, Issue 24, 2015

C-1 building blocks are ubiquitously employed in organic synthesis. Based on the recent trend in this field, the advances in the synthesis of heterocycles using unconventional C-1 building blocks are highlighted.

The significance of main group metallic Lewis acids such as LiCl, MgCl2, AlCl3 on the formation and reactivities of Grignard reagents are best demonstrated by recent quick development of their diverse synthetic techniques and versatile reactivities towards various electrophiles. Although substantial progress has been made especially on the selective formation of carbon-metal bonds employing lithium chloride as the activ Read More

The alternating copolymerization of carbon dioxide and epoxides to give polycarbonates and cyclic carbonates has attracted the attention of researchers since it fixes CO2, a green house gas, chemically. This review makes an attempt to present a critical assessment of the available information particularly on copolymerization of propylene oxide and CO2 and thereby indicates the areas and gaps where further work i Read More

Bischler-Napieralski (B-N) reaction is undoubtedly one of the most powerful methodologies in organic synthesis for the construction of isoquinoline moieties as important heterocyclic compounds. It has also captured great attention in the total synthesis of naturally occurring compounds such as alkaloids, which mostly and particularly bear isoquinolines as scaffold in their structures. The present review is focused on and highlighte Read More