Current Organic Chemistry - Volume 18, Issue 5, 2014

Stereoselective synthesis of new C-C bonds is one of the main objectives of organic chemistry. In this field, silyl activation of alkenes is a useful organic tool in a huge number of Lewis acid promoted reactions due to the ability of the silicon to stabilize neighboring cations. This review summarizes the Lewis acid promoted addition of silyl enol ethers and allylsilanes to epoxides and other small oxygenated rings, which h Read More

Biomass derived carbohydrates and related raw materials are the most abundant renewable resources available which have great potential as bio-fuels and chemical building blocks for a diverse range of applications. They can reduce to a large extent our over dependence on fossil-fuel resources. Over the past decade, various acid and/or base catalysts have been used to transform biomass resources into different kinds Read More

This review presents a survey of literature reports dealing with both site and peri-selectivities in cycloaddition reactions of nitrilimines with multifunctionalized dipolarophiles. The literature results covered in this review, during the period from 1970 to mid 2013, demonstrate that chemo-selectivity plays an important role in synthetic design.

Carbohydrate microarrays are powerful tools to investigate the recognition events because of carbohydrate-protein interactions in high-throughput fashion. Some methods have been utilized to immobilize the nonderivatised or derivatised carbohydrates on support surfaces in the microarray mode. Because polysaccharides have the hydrophobic interactions, polysaccharide arrays are very easy to construct by non-covalently i Read More

CO2 is regarded as the primary greenhouse gas. Its conversion into reusable fuels over photocatalysts attracts much attention and many papers are published in recent years. The photocatalytic activity is an important term in evaluating the photocatalyst performance, which is not only determined by types of photocatalysts, but also closely related with the other factors, such as the sizes, morphologies, exposed crystal f Read More

Synthesis and characterization of some novel phosphonate derivatives as uPA inhibitors have been conducted. HOMO and LUMO energies, NPA charges, electrophilicity index and vibrational frequencies were calculated for the current and previously reported phosphonates. Based on the calculated properties, the results obtained indicate that the novel compounds are expected to be more potent than other phosphonates.