Current Organic Chemistry - Volume 14, Issue 1, 2010

The Rhizopus spp., in particular Rhizopus oryzae, are among the most frequently used whole cell biocatalysts. The fungus is known to catalyze the bioconversion of various reactive and non-reactive substrates with high regio- and stereoselectivities. The range of products obtained from these reactions has been attributed to the substrate binding modes within the enzyme's active site. More recently, an active site model has be Read More

In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.

This review deals with synthesis and reactions of 2-acetylbenzofurans. Some of these reactions have been applied successfully to the synthesis of biologically important compounds. The main purpose of this review is to present a survey of the literature on 2-acetylbenzofurans chemistry and provides useful and up-to-date data for their applications since such compounds have not been previously reviewed.

Modern organic synthesis requires easily obtainable synthetic building blocks that can be manipulated without the need of severe reaction conditions and that show high chemical versatility so that they can be employed in diverse synthetic processes. β- Nitroacrylates are a class of electron-poor alkenes having two electron-withdrawing groups in α- and β-positions. This peculiarity makes their chemical behaviour mo Read More

Hybrid organic-inorganic solar cell was fabricated by thin film of nanocrystalline magnesium phthalocyanine, MgPc, on ptype Si substrates using the conventional thermal evaporation technique. The measured electrical parameters were used to determine the predominat conduction mechanisms of these heterojunctions in the temperature range 298 to 373 K. The dark forward current was found to be increased exponentially with Read More