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- ISSN: 1385-2728
- E-ISSN: 1875-5348
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Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds
- Source: Current Organic Chemistry, Volume 14, Issue 1, Jan 2010, p. 15 - 47
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- 01 Jan 2010
Abstract
In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.
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