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Volume 3, Issue 1
  • ISSN: 2666-8629
  • E-ISSN: 2666-8637

Abstract

Objective

An acne is a frequent form of skin condition brought on by an overproduction of the particular oil “sebum”, which is produced by the sebaceous gland. This oil accumulates in the follicles and causes the swelling of pores. Many microbial species such as . are responsible for acne directly or indirectly. The aim of this study was to synthesise the herbal gel of tea tree oil obtained from the plant

Material and Methods

The gel was prepared using Carbopol-940 as a gelling agent using the swelling method and parameters like spreadability, extrudability, pH, were also determined. Zone of inhibition (ZOI) was estimated with renowned standards (Ciprofloxacin and fluconazole).

Results

Studies revealed that the gel was highly effective against the selected species except fungal strains. ZOI was observed ranging from 1.6 ± 0.01 mm to 14.9 ± 0.43 mm. The maximum ZOI was observed (14.9 ± 0.43) against . The physical properties of the gel satisfied the standard parameters.

Conclusion

The herbal gel was found to be highly promising activity against bacterial species associated with acne in a concentration-dependent manner, but more research is needed.

© 2025 Bentham Science Publishers
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2023-10-11
2025-01-24

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/content/journals/cff/10.2174/0126668629261287231002101556
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Formulation and Antimicrobial Screening of Tea Tree Oil Gel
Curr Func Foods 3, E111023222098 (2025); https://doi.org/10.2174/0126668629261287231002101556
/content/journals/cff/10.2174/0126668629261287231002101556
/content/journals/cff/10.2174/0126668629261287231002101556
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  • Article Type:     Research Article
Keyword(s): acne; minimum inhibitory concentration; sebaceous gland; skin diseases; Staphylococcus aureus; Tea tree oil gel

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