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- Volume 20, Issue 2, 2025
Current Drug Therapy - Volume 20, Issue 2, 2025
Volume 20, Issue 2, 2025
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Exploring the Efficacy of Herbal Medications in the Treatment of Parkinsonism: A Mini Review
Authors: Pravin Kumar, Ritik Chaudhary and Mahendra Singh AshawatBackgroundOver 10 million people worldwide are affected by the chronic neurodegenerative condition of Parkinson's disease. Dopaminergic neurons in the Substantia Nigra area of the brain are gradually lost as a result. Herbal medicine, which have its roots in ancient cultures, uses medicinal herbs to treat illnesses and advance general health. There is considerable interest in researching the possibilities of herbal me Read More
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Role of Conventional and Novel Classes of Diuretics in Various Diseases
Authors: Nitika Yadav, Neelottama Kushwaha, Swatantra K.S. Kushwaha and Priyank YadavDiuretics are advised as the initial course of action for hypertension because they are successful in lowering hypervolemia and resolving electrolyte abnormalities. The most popular diuretics are included with their main characteristics in this summary. The primary line of treatment for common cardiovascular and non-cardiovascular diseases is diuretics. Patients with hypertension, oedema, heart failure, as well as a variety of ren Read More
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CMC and QMS Regulatory Requirements and Challenges for mRNA-based Vaccines
Authors: Surbhi Tyagi, Vikesh Kumar Shukla and Sandeep AroraBiopharmaceuticals differ significantly from chemical drugs, and thus their CMC regulatory compliance is distinct from them. The development of biologicals, like mRNA vaccines, holds promise for preventing infectious diseases and generating an antigen-specific immune response. These vaccines are a better option than traditional vaccination methods because of their significant potency and swift and affordable manufac Read More
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Analysis of Clinical Pharmacsology Research Publication in Doping and Anti-Doping: A Scientometric Study
The importance of medical professionals like clinical pharmacologists in the field of sport medicine lies in their expertise in doping and anti-doping. There is a need to identify the expertise globally and understand the pattern of research being done in this area. This helps for future collaborative and combined policies, irrespective of any borders. The purpose of this study was to conduct a scientometric examination of bibliograph Read More
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Antimetastatic Drug, Pharmacologic Challenge and Opportunity
Authors: Da-Yong Lu and Ting-Ren LuCancer is a complex and high-mortality disease in the clinic. Cancer metastasis leads to most cancer deaths. The therapeutics for cancer metastasis are greatly unsatisfactory now. Despite different types of antimetastatic agents and drugs have been reported, 90% of patients die in 5 years after metastatic nodules at secondary sites have been found.Many pharmacologic challenges and opportunities for current metas Read More
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Improving Women's Health and Immunity: A Thorough Mapping Micronutrients and Dietary Recommendations
In particular, throughout life, women's health depends on having an ideal micronutrient level. Thus, pregnancy outcomes and the long-term health of a woman's offspring are significantly influenced by her physical and nutritional well-being during the preconception stage. Various nutrients are required in sufficient amounts to fulfill the requirements at the various phases in the life of females. Our analysis of the state of nutrition Read More
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Formulation and Evaluation of Hard Lozenges by Using Garlic Tincture
BackgroundLozenges are one of the more well-liked and inventive oral confectionery products in the market. The lozenges also act as solid medications that are flavored, sweetened, and meant to be sucked into the mouth/pharynx or held over that cavity. Garlic contains anti-microbial agents which help to reduce the impact of cough and reduce it.AimsThe goal of the current research is to formulate and investigate her Read More
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Machine Learning Prediction and Simulation of Drugs Targeting GSK-3β in Breast Cancer
Authors: Gayatri Munieswaran, Nandha Kumar Subramani and Subhashree VenugopalIntroduction and ObjectiveBreast cancer ranks as the second-most prevalent cause of death among women worldwide, with particularly elevated mortality rates in India. Breast cancer’s origin involves biochemical pathway alterations influenced by tumor-inducing proteins. Research has highlighted glycogen synthase kinase-3 beta (GSK-3β) as a crucial protein that regulates the expression of various genes in the cell cycle Read More
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In-vitro Lipolysis, Stability and Pharmacodynamic Study of Cilnidipine Loaded Self-emulsifying Drug Delivery System
Authors: Renu Kadian and Arun NandaAimsThe aim of this research work was to investigate the potential ability of cilnidipine-loaded-Self-Emulsifying Drug Delivery System (SEDDS) to improve the solubility and oral bioavailability of cilnidipine.BackgroundThe therapeutic value of drugs is constrained by the low oral bioavailability of BCS class II drugs. In order to improve the solubility and oral bioavailability of poorly water-soluble drugs, SEDDS are frequently utilised. Read More
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Anti-Inflammatory and Wound Healing Potential of Comphora Wightii, Herbal Ointment on Wistar Rats
Authors: Ishu Garg, Neelam Singh, Ishika Sharma, Jayeeta Dhingra and Kartik KumarBackgroundA herbal approach to Guggulu (Commiphora wightii), as an anti-inflammatory and wound healing agent is anticipated. Phyto-constituents Guggulusterone, Naringenin, and myrrhanol were reported for the anti-inflammatory activity of Guggulu. Studies suggests, that sesame oil (Sesamum indicum L.) and Ratanjot (Arnebia nobilis) also act as potent anti-inflammatory agents. A combination of all three Read More
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Comparative Evaluation of Cefixime Microspheres Utilizing a Natural Polymer and a Synthetic Polymer
Authors: Deepshi Arora, Yugam Taneja, Anjali Sharma, Prerna Sharma, Jatin, Kumar Guarve, Nidhi Rani and Inderjeet VermaBackgroundMicrospheres are naturally biodegradable, free-flowing powders with a particle size of less than 200 micrometres that are comprised of proteins or synthetic polymers. Using microspheres is a reliable strategy to ensure that the drug is accurately delivered to the target area and that the right concentration is kept there without having any unfavourable side effects.ObjectivesThe objective of the present study was to cr Read More
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Volumes & issues
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Volume 20 (2025)
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Volume 19 (2024)
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Volume 18 (2023)
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Volume 17 (2022)
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Volume 16 (2021)
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Volume 15 (2020)
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Volume 14 (2019)
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Volume 13 (2018)
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Volume 12 (2017)
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Volume 11 (2016)
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Volume 10 (2015)
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Volume 9 (2014)
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Volume 8 (2013)
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Volume 7 (2012)
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Volume 6 (2011)
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Volume 5 (2010)
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Volume 4 (2009)
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Volume 3 (2008)
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Volume 2 (2007)
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Volume 1 (2006)
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