Current Bioactive Compounds - Volume 21, Issue 1, 2025

BackgroundBiosurfactants are very important amphiphile compounds due to their interesting advantages such as low toxicity, biodegradability and also their many biological properties.MethodsIn the present study, antimicrobial and anti-imflammatory activities were evaluated to determine the biological proprieties of biosurfactant BLA 2906 produced by Alcaligenes aquatilis YGD 2906 using different assays. Screening and optimi Read More

BackgroundNimodipine is a highly lipophilic anti-hypertensive drug having 13% oral bioavailability (log P 3.41). Nimodipine is a prominent calcium channel blocker that must be given intravenously for an extended period of time (1-2 weeks) in order to treat cerebral vasospasm. It might be possible to substitute a sustained-release biodegradable formulation for the ongoing intravenous infusion used in this traditional therapy. Read More

IntroductionBy condensing 2-aminothiazole and phenacyl bromide, a novel
catalyst-free synthetic approach for the synthesis of imidazo[2,1-b]thiazole derivatives has been
developed.MethodsIn this work, aloe vera/water (3:2) is used as a reusable, environmentally benign, green-promoting media to synthesize desired products. This method enables the synthesis of a diverse range of aryl-substituted imidazo[2,1-b] Read More

BackgroundThe constant increase in global onion production escalates the 
generation of onion peel waste. For instance, globally, >50 lakh tons of onion waste are generated annually.MethodsIts objectionable odor precludes its use in agriculture or disposal as landfilling presents environmental issues. Previous studies show that two major flavonoids, quercetin and its
glycosides (spiraeoside), have been identified in abundance in Read More

BackgroundThe study addresses the underexplored realm of cytotoxicity evaluation involving binary mixtures of Passiflora caerulea leaf extracts and Titanium nanoparticles (TiO2NPs). The focus lies on understanding the combined effects of these components on cancer cells (A549, U937, and HeLa).MethodsIn vitro cytotoxicity assessments were employed to evaluate the toxicity of P. caerulea leaf extracts, TiO2NPs, and their c Read More

Environmental pollutants pose a serious risk to human health and are involved in the emergence of many diseases and disorders. In recent years, the research for efficient defence against these pollutants has focused much interest. Natural flavonoid apigenin in various fruits and vegetables has shown great defence against environmental toxins. This review aims to summarize the current knowledge regarding the protective Read More

BackgroundThe encapsulation technique is an effective method for coating bioactive molecules and protecting them against various technological treatment conditions during production processing.ObjectiveThe aim of this study was to optimize the encapsulation conditions of phenolic compounds extracted from Malabar nut (Justicia adhatoda L.) leaves by alginate emulsion-gelation approach using response surface me Read More