Current Bioactive Compounds - Current Issue

Psoriasis is a long-term inflammatory skin condition that is caused by a typical proliferating keratinocytes that emerge as substantial scaly, red and fragile patches. Although in current therapy, conventional treatments usually involve topical corticosteroids, immunosuppressants, and phototherapy, these therapies have restrictions and undesirable consequences. Nanotechnology provides significant novel opportunities Read More

IntroductionA 9-aminoacridine derivative has anticancer properties against several types of cancer cells, including colon, breast, pancreatic, lung, and renal cell carcinoma. It triggers apoptosis by stopping the cell cycle in the S phase and inhibits the activity of topoisomerase. So, the present study deals with the synthesis and anti-cancer activity of some of the acridine derivatives.MethodsThe novel set of N-(acridin-9-yl)-N-(2-s Read More

BackgroundVarious Mentha species are cultivated all over the world due to their aroma and valuable therapeutic constituents. Along with its traditional use as a food flavor, it is well-established folklore medicine for treating digestive and cardiovascular problems. Mentha spicata L. is a perennial, aromatic herb belonging to the Lamiaceae family. M. spicata leaves have been used in traditional systems of medicines for tr Read More

Skin cancer has become the fifth most frequently reported form of cancer worldwide, imposing significant economic and public health challenges. Over the course of the last ten years, there has been a significant increase in the application of Nanoparticles (NPs) as a method of therapeutic administration to target skin cancer. The information has been gathered from many online databases, such as Scopus, Pubmed, Science Read More

Nowadays, cancer treatment is currently limited to surgery, chemotherapy, and radiation, which carry the risk of damaging the normal tissue of the body and incomplete removal of the cancerous cells from the body. Thus, the Nano technique offers a great means to target therapies directly on cancerous cells and neoplasm. Moreover, because nano-based formulations of polyphenolic curcumin show a major effect on cancer Read More

BackgroundGlycerolates of biogenic elements are of interest because of their pharmacological activity. Some of them are used as active substances in agents for topical application and as biocompatible precursors in sol-gel synthesis of bioactive materials.ObjectiveIn this work, morphostructural feature, ability to hydrolyze, and the pharmacological activity of previously synthesized iron(III) monoglycerolate were Read More

BackgroundDue to the fact that animal parasitic diseases often occur in the form of mixed infections, it is necessary to use complex drugs with a combination of active substances that act against different classes of helminths. Fenbendazole has a wide spectrum of nematocidal action and is less effective against cestodes. Considering that sheep are often infected with both gastro-intestinal nematodes and cestodes, a comple Read More