Current Bioactive Compounds - Volume 19, Issue 4, 2023

Background: Herbal medicines have been derived from different parts of the plants including roots, bark, seeds, flowers, and leaf. Human beings have been using herbal medicine and their derived phytochemicals for the treatment of human health complications since ancient times. Presence of different classes of phytochemicals is responsible for different pharmacological activities of herbal drugs and their derived products. Read More

Psoriasis is an autoimmune skin condition that is also inflammatory and proliferative. Psoriasis is caused by the activation of T-cells and is distinguished by prominent, drab-red, or peach-pink tight patches with silvery scales on the skin. In recent years, there have been some significant advances in the study of the etiology of inflammatory skin diseases such as psoriasis. The nanotechnology-based novel formulation prov Read More

Background: A new series of malonic acid-based hydrazide derivatives (BPMPDH, 2HPMPDH, 3HPMPDH, 4HPMPDH, DMPDH) were successfully synthesized by the reaction of malonic ester hydrazide with various aldehydes like salicylaldehyde, benzaldehyde, 4-hydroxy benzaldehyde, 3-hydroxy benzaldehyde and formaldehyde. Objectives: Furthermore, metal complexes of prepared hydrazide derivatives were prepared Read More

Background: Nature-based pharmaceuticals are now becoming an integral aspect of toxic-free healthcare therapies. Diosgenin (DN), a unique phyto steroidal sapogenin, seems to be explicitly employed as a core ingredient in countless traditional and patented Chinese medicines owing to its epic multilayered therapeutic treasure. Objective: The prime intent of the current study was to probe the hepato- and nephro- ameliorat Read More

Background: Solidago virgaurea (Asteraceae) has been used for more than 700 years for treating cystitis, chronic nephritis, urolithiasis, rheumatism, and inflammatory diseases. However, the antidiabetic activity of Solidago virgaurea has been rarely studied. Methods: Three extracts of Solidago virgaurea were prepared, and their antidiabetic potentials were evaluated by various cell-free, cell-based, and in vivo studies Read More

Background: Coccidiosis is a common infection among birds that is caused by Eimeria spp. (Protozoa, Phylum Apicomplexa). Eimeria is transmitted fecal-orally and replicated in the intestines. Coccidiosis causes economic losses and increases birds’ susceptibility to other diseases. Methods: In this study, the broilers were experimentally infected by Eimeria tenella and then treated with Sulfaclozine and Iberogol. Birds were randomly Read More

Aim: The present study aimed to investigate the bioavailability of curcumin conjugated with isoleucine. Background: Curcumin has various health beneficiary properties; however, it is poorly bioavailable because of its insolubility in water, poor absorption and quick systemic elimination. Hence, any approach that could improve bioavailability is necessary. Objective: The objective of the present study is to examine whether the bio Read More

Psoriasis is a multifaceted inflammatory dermatological skin disease characterized by Tcell (T-lymphocyte) activation, hyperproliferation, and abnormal epidermal keratinocyte differentiation. Natural bioactive agents from plants including Psoralea corylifolia, Nigella sativa, Curcuma longa, Capsicum annum, Smilax china, Woodfordia fructicosa, and others have recently gained a lot of attention for their anti-psoriatic properti Read More