Current Bioactive Compounds - Volume 19, Issue 10, 2023

Background: Tuberculosis (TB) has long been the major infectious cause of mortality, ranking higher than HIV/AIDS as the most common cause of death from a single infectious agent worldwide. The EchA6 target of mycobacteria plays a vital role in synthesizing an important component of the mycobacterial outer membrane. The failure of TB treatment has prompted the investigation of novel anti-tubercular drugs. Objective: T Read More

Aims: This study aimed at developing bioactive peptides by optimization of the enzymatic hydrolysis process of protein from tilapia fish skin waste (Oreochromis niloticus, Linnaeus 1758) using alcalase 2.4.L. Background: Natural bioactive peptides are considered to have low toxicity and therapeutic properties as antioxidants. Objective: The conditions of protein hydrolysis obtained from tilapia fish skin waste (Oreochromis Read More

Introduction: Cardiovascular disorders are the most prevalent and life-threatening conditions affecting human beings. Therefore, this study aimed to assess the cardioprotective effect of P. rubra leaves. Aim: Plumeria rubra L. has been used for ages in alternative/traditional systems of medicine for several conditions, such as arthritis, toothache, pruritus, asthma, dysuria, gonorrhoea, diabetes, and various types of inflammation. Read More

Background: In addition to being one of the deadliest tumors, breast cancer is also one of the most difficult to cure. Due to the serious side effects of current breast cancer treatments and the rise in drug resistance, current drugs are losing their effectiveness. Potential Natural Bioactives: Bioactive natural compounds target various pathophysiological pathways involved in the development and progression of cancer and he Read More

Background: Sorghum, a wonder millet, is well known for its beneficial phytochemical profiles. In comparative terms, juice from sweet sorghum has better commercial potential as syrup in several food-based applications. Various sweet sorghum varieties differs in their profile of various phytochemicals, which can impact the commercial potential of sweet sorghum juice. Methods: Our previous works on cultivars develope Read More

Aim: The primary goal of this study is to create a novel naproxen sodium-loaded ethosome drug delivery system for improving bioavailability, solubility and optimize using a statistical approach. Background: Naproxen sodium (i.e., a non-steroidal anti-inflammatory drug) is chosen as the first line of treatment for rheumatoid arthritis and ankylosing spondylitis. However, naproxen has side effects, such as bronchospasm, a Read More

Psoriasis is a hereditary, immune-mediated illness that can affect the skin, joints, or both. The condition frequently requires the treatment of a wide group of specialists with a variety of specialties. Numerous difficulties are presented by psoriasis, such as its high prevalence, chronicity, disfigurement, disability, and related comorbidities. Natural treatment of psoriasis can be provided by flavonoids and furanocoumarins. Read More

Inflammation is a part of the biological response of body tissues against harmful stimuli, such as damaged cells, pathogens, irradiations, and toxic compounds. Numerous treatments, including anti-inflammatory drugs that treat the condition of inflammation, are available for its management. Because of the severe adverse effects associated with synthetic medications, phytotherapy may be a promising and effective approach Read More