Current Bioactive Compounds - Volume 19, Issue 3, 2023

The aim of this work was to conduct an in vitro assessment of the possible cytotoxic effects of homeopathic drugs and consider possible mechanisms. Background: Homeopathy is still widely used as a complementary (alternative) medicine in different countries throughout the world. However, the method raises a lot of scientific debate about its effectiveness and mechanisms of action. This is especially true concernin Read More

Background: Astragalus gossypinus Fisch. is one of the Astragalus (Leguminosae) species that has been used in traditional medicine due to its phenomenal pharmacological and biological activities. Objective: In this research, the mutagenicity, anti-mutagenicity, and antioxidant potential of two different extracts of root (chloroform and ethyl acetate) and chloroform extract of aerial parts of Astragalus gossypinus were investi Read More

Background: Diabetes is a problem of public health; in consequence, the increasing prevalence of both diseases needs more functional food products with efficiency and low cost to support treatment. Methods: Flavonoids from the herbal formulation of Portulaca oleracea, Zingiber officinale, and Tamarindus indica were extracted by ultrasound-assisted extraction technology, where several experiments were conduct Read More

Background: The Adiantum lunulatum is a medicinally important pteridophyte used to treat inflammatory related diseases. The phytochemical profile of this plant is poorly investigated. Objective: Here, we screened the nonpolar phytochemicals and their interactions with cyclooxygenase 2 (COX-2) enzyme (inflammation), transient receptor potential cation channel V member 1 (TRPV1), and transient receptor potential chan Read More

Background: Prunus armeniaca L. is widely cultivated around the world. High consumption of its fruit produces a large number of apricot kernel shells. The valorization of this byproduct in terms of polyphenol compounds seems to be important. Objective: This study aimed to optimize the extraction of phenolic compounds from apricot kernel shells by different extraction techniques by studying the effects of different param Read More

Peptides are small biomolecules that act as bioactive or host defense molecules. These peptides have a significant role in medicine because of their broad spectrum antimicrobial properties. Marine sources are the largest supply of peptides and natural small molecules since they represent half of the total global biodiversity. Among the different crab species, the horseshoe crab is widely used for extracting the peptides. The horses Read More

Nanometrology has been considered a key to the future of nanotechnology recently. It is particularly important for nanoparticle market development that is commonly applied in different areas of science. The adoption of nanotechnologies in food and agrochemical industries represents a new frontier, with particular regard to plant defence against pathogen agents. Nanometrology deals with a broad range of Read More

To combat the escalating antimicrobial resistance, we must constantly develop new medications. Recently, scientists more focused on endophytes to search for novel antimicrobial natural products. Endophytes are explored as 'bio-factories' of natural bioactive therapeutic compounds. These are microbes exhibited in plant living tissues without causing any harmful effect. Many therapeutic compounds isolated from endophytes Read More

Neem (Azadirachta indica), a Meliaceae family member, is a rapidly growing tropical evergreen tree with a thick, branching trunk. It has been used for hundreds of years in traditional Indian medicine as a home cure against numerous human illnesses in the Indian and African continents. Different components of the plant, including the flowers, leaves, seeds, and bark, have been used to treat both acute and chronic huma Read More

Background: Diabetes is a chronic disease affecting more than 8.5 % adult population in the world. Among various issues caused by diabetes, wound healing is a major cause of concern. Objective: Injuries are most common, and can be caused normally by abrasion, laceration (cuts), injury, etc. But in diabetes, they do not heal so easily and cause problems. It can be due to a compromised immune system, neuropathy, poor Read More