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- Volume 11, Issue 3, 2021
Natural Products Journal, The - Volume 11, Issue 3, 2021
Volume 11, Issue 3, 2021
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Barleria prionitis L.: An Illustrative Traditional, Phytochemical and Pharmacological Review
Authors: Sabyasachi Banerjee, Subhasis Banerjee, Gaurab K. Jha and Sankhadip BoseBarleria prionitis, a small perpetual, prickly shrub, belongs to the family Acanthaceae, normally called “porcupine flower” or “Vajradanti” with a lot of vernacular names. It is an indigenous herb of Southern Asia and some regions of Africa. The therapeutic use of leaf, flower, stem, seed, shoot, root and in certain cases complete herb of B. prionitis against numerous disorders including cough, fever, jaundice, asthma, severe pain Read More
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Mysterious World of Lichens: Highlights on Their History, Applications, and Pharmaceutical Potentials
Background: Lichens play an important role in many ecosystems and exist as a symbiotic association between fungi and algae or cyanobacteria. This symbiosis results in the production of unique secondary metabolites known as lichen substances, which arise within the thalli and are typically in crystal form on the surface of the fungal hyphae. Recently, lichens and their secondary metabolites have been receiving increased att Read More
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A Comprehensive Review of the Aizoaceae Family: Phytochemical and Biological Studies
More LessThe Aizoaceae “ice plant” family, is one of the neglected plant family despite its promising phytoconstituents. It includes approximately 135 genera and 2499 succulent species distributed throughout the tropics and subtropics worldwide. Many of the species in this family have a long history in traditional medicine, and many phytochemical and biological studies have attempted to confirm the folk uses of these plants. This revie Read More
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Utilization of Plant Derived Metallic Nanoparticles for Biomedical Applications
Authors: Akanksha Sharma, Pramod K. Sharma and Rishabha MalviyaAim: The aim of the manuscript is to summarize various biomedical applications of metallic nanoparticles that are synthesized using herbal components. Methodology: Various search engines such as google, sciencedirect, scopus etc. were utilized for the literature survey. The literature survey was focused on the different parts of plants like leaves, stem, root, fruit and flowers as a source of therapeutic active component Read More
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Physicochemical and Biological Aspects of Curcumin: A Review
Authors: Priyanka Kriplani and Kumar GuarveBackground: Curcuma longa L. is worldwide investigated as the well known indian spice by virtue of its principal constituent, curcumin. Objective: The objective of this review is to study the biosynthetic pathway, extraction process, chemistry, various analytical methods for identification of curcumin and its effect on biological system. Methods: Current prose and papers emphasizing the biosynthesis, extraction methods, anal Read More
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Anti-Inflammatory Agents Produced from Plant Latex
Plants have been the main source of molecules for the treatment of diseases over the years. They have been used in traditional medicine based on experience and practice. Many molecules from plant latex have been isolated, identified and tested for pharmacological activities, including reduction of inflammation. This review provides an overview of the latexes released from different plant species and their anti-inflamma Read More
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Deinbollia pinnata: Isolation and Characterization of Some Phytochemicals from Aerial Parts and their Antioxidant Potential
Authors: Yakubu Rufai, Norazah Basar and Aliyu SaniBackground: Deinbollia pinnata belonging to Sapindaceae family are known as medicinal plants for the treatment of human diseases. Because of human over-exploitation, the choice of phytochemicals re-search and screening was made to add to the available compounds and ethno-medicinal records. Objective: To investigate phytochemicals and their antioxidant activities. Methods: Antioxidant assay (DPPH, ABTS, FRAP) activiti Read More
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Evaluation of Cytotoxic Mechanisms of Clinacanthus Nutans Extracts in Cancer Cells
Background: The preparations of commercially available Clinacanthus nutans (Burm.F) Lindau (Acanthaceae) (CN) leaf are gaining attention as an alternative cancer treatment, particularly in South East Asia. Multiple studies have suggested that CN has potential anticancer activities; however, the mechanism of these activities has remained elusive. Objective: This study evaluated the cytotoxic mechanisms of CN extracts in can Read More
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Quality Evaluation of the Tugaksheeree Samples by ATR-FTIR Spectroscopy Using Multicomponent Analysis
Authors: Nikunj D. Patel and Niranjan S. KanakiBackground: Numerous Ayurvedic formulations contain tugaksheeree as a key ingredient. Tugaksheeree is the starch gained from the rhizomes of two plants, Curcuma angustifolia Roxb. (Zingiberaceae) and Marantaarundinacea (MA) Linn. (Marantaceae). Objective: The primary concerns in quality assessment of Tugaksheeree occur due to adulteration or substitution. Methods: In the current study, Fourier Transform Infrared Read More
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Analyzing Phytochemicals as Inhibitors of Diabetes Mellitus 2 Causing Proteins based on Computer-Aided Drug Discovery Protocols
Authors: Sobia N. Chaudry, Waqar Hussain and Nouman RasoolBackground: Diabetes Mellitus type 2 is one of the complex diseases, affecting people both in developed and developing countries. Plant extracted compounds known as phytochemicals are worthy because they have various medicinal properties. Objective: The present study aimed at the in silico discovery of novel potent inhibitors against Diabetes Mellitus type 2. Methods: A total of 2750 phytochemicals from various medicin Read More
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Effect of Umbelliprenin on Antinociceptive Activity of Morphine in a Rat Model of Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve
Authors: Samad Nazemi, Faranak Jafari, Bahareh Amin, Omid Gholami, Marzieh Kafami and Mohammad-Shafi MojadadiObjective: Although morphine is among the first-line medicines for the treatment of neuropathic pain, evidence has shown that the morphine efficacy gradually decreases and tolerance can occur. Regarding many reports concerning the antinociceptive and anti-inflammatory properties of umbelliprenin (UMB), this study aimed to investigate the effect of UMB on antinociceptive activity of morphine in a rat model of neuropa Read More
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Octabenzone Isolated from Saharan Myrtle Leaves (Myrtus nivellei)
Authors: Amira Mansour, Ghania Rahili, Orsolya Roza and Smain ChematBackground: The Algerian Saharan plants are plants of terrestrial origin, which during their evolution have adapted to the Algerian south ecosystem. By their particular ecological and evolutionary position, it is possible that these endemic plants also selected specific secondary metabolites with original chemical and biological characteristics. Objective: Phytochemical investigation of ethyl acetate and n-butanol e Read More
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Effect of Traditional Herbal Formulation on Experimental Models of Ulcerative Colitis
Aims: Evaluation of the effectiveness of herbal formulation consisting of Morinda citrifolia L, Artemisia annua L, Glycyrrhiza glabra L and Ocimum basilicum L, in treating ulcerative colitis. Objectives: Assessment of the effect of herbal formulation on the indomethacin-induced ulcerative colitis based on serum lactate dehydrogenase (LDH) level, tissue myloperoxidase (MPO) activity and colonic glutathione (GSH) content and ma Read More
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Evaluation of Anti-Diabetic and Anti-Hyperlipidemic Activity of Isolated Bioactive Compounds of Leaves of Annona reticulata Linn.
Authors: Kalyani Pathak, Aparoop Das, Anshul Shakya, Riya Saikia and Himangshu SarmaBackground: The leaves of Annona reticulata Linn. have been traditionally used by the tribes of Assam as a source of medicine to mitigate a range of health ailments, including diabetes and obesity. Objectives: The current study aimed to evaluate the anti-diabetic and anti-hyperlipidemic potential of bioactive fractions isolated from the methanolic extract of Annona reticulata Linn. leaves using Nicotinamide + Streptozotoc Read More
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Anti-allergy Effect of Sulfated Polysaccharide from Sargassum polycystum on Dinitrofluorobenzene Induced Allergic Contact Dermatitis in Mice
More LessBackground: Sargassum polycystum C. Agardh has potent antioxidant and antiinflammatory properties. However, its anti-allergic effect has not yet been reported. In this study, we investigated the anti-allergic effects of sulfated polysaccharide of S. polycystum (SPSP) in Dinitrofluorobenzene (DNFB)- induced allergic contact dermatitis animal model. Methods: SPSP was extracted through the hot water extraction method and w Read More
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