Natural Products Journal, The - Volume 11, Issue 5, 2021

Background: Helicteres hirsuta has been used traditionally as a useful agent for hepatoprotective treatment. The aim of the current study is to isolate chemical constituents from the EtOAc extract of H. hirsuta stem and evaluate the capacity of the isolated compounds against hydroperoxide damaged rat liver cells. Methods: Column chromatography was used for phytochemical isolation whereas MTT method was applied for i Read More

Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological con Read More

Arctium lappa or burdock (Compositae family) is a perennial plant, native to Europe, Northern Asia, and North America. Burdock roots are known as detoxifying herb to clear toxins from the bloodstream. It seems that its effects are on the liver functions as it is main part of the body for detoxifying the bloodstream. The aim of this review article was to evaluate the potency of burdock in the management of liver functions Read More

Tetraterpenoids comprise of a large family of C 40 polyene, obtained from plants, fungi and bacteria. Their colouring properties have been employed to use as a natural colorant in the pharmaceutical industries. These exist as an attractive target of research because of their easy availability and plentiful health benefits in cardiovascular diseases, cancer, age related degenerative diseases, macular degeneration, a Read More

Aim: The purpose of this review paper is to elaborate many nano-formulations of Rosemary which are used against many diseases and also explain the Pharmacological activity of phytocompounds of Rosemary and detail about the applications and uses of Rosemary in many fields. Objectives: Rosemary (Rosmarinus officinalis L.) is a medicinal herbal plant; their leaves are used in Europe, America, and Asia as a food additive. It Read More

Coumarins, a natural class of compounds, firstly isolated from Tonka beans, are found in various medicinal herbs. This class of compounds has been reported of remarkable biological and pharmacological applications, including antimicrobial, anticoagulants, anti-inflammatory as well as cancer. Additionally, coumarins have revealed significant inhibition of different human cancers viz bladder cancer, lung cancer, prostate Read More

Aim and Background: Amytriptiline (AMY), an antidepressant, is used in the treatment of neuropathic pain. However, with limited therapeutic benefits and side effects of AMY, it is not helpful to the majority of the neuropathic pain patients. Gallic acid (GA) is a polyphenolic product with potential antioxidant effects, useful in neuropathic pain. Objective: The purpose of the study was to investigate the improved neuropathi Read More

Background: The emerging public concern regarding the quality of drinking water has led to an increased interest in household water treatment systems. Many systems reduce contaminants effectively in laboratory tests, at least to some degree, but for the vast majority, their effects in actual use are not investigated. Objective: To test the effectiveness of an in-home water filter system (AcalaQuell® Swing) in reducing health p Read More

Aim: The aim of the present study was the establishment of a process for the extraction of phytochemicals from Ficus racemosa. Background: Ficus racemosa is an underutilized crop containing numerous phytochemicals having the potential to play a significant role in food and nutritional security. However, it has lower consumer acceptability because of its taste and presence of fig wasps. In these situations, extraction of t Read More

Background: The Lamiaceae (Labiatae) family is one of the most diverse and widespread plant families in terms of ethnomedicine and its medicinal value is based on the concentration of the volatile oil present in it. This family is important for flavor, fragrance and medicinal properties. Many plants belonging to this family have indigenous value. Methods: The essential oil of Plectranthus gerardianus Benth. (Lamiaceae) was an Read More

Background: Natural products play a significant role in the drug discovery process due to the presence of a large variety of bioactive compounds. Objective: The present study aims to isolate the essential oil from Salvia Fruticosa (SF), Lavandula Intermedia (LI), and Rosmarinus Officinalis (RO) with identification of the chemical composition of the oils and to investigate the antioxidant, antifungal and antibacterial activities. Metho Read More

Aim: The present study aims at explaining the epidemic situation in India for COVID-19 and forecasting the expected rise in the positive cases in India. Objective: This study will be useful for Government authorities and Medical Practitioners in assessing the trends for India and preparing a combat plan with stringent measures. This research would also be useful in predicting outbreak numbers with greater precision for peop Read More

Background: Protium heptaphyllum (Aubl.) March resin is accepted as an analgesic, healing, expectorant, anti-inflammatory, antinociceptive and gastroprotective agent. However, there are no specific studies on leaves of this plant. Objective: This study identified the chemical composition and biological activity of crude ethanolic extract (EE) and ethyl acetate (EA) fraction from P. heptaphyllum. Methods: Mice were intoxicated w Read More

Background: Spondias pinnata (L. F.) Kurz is a well-known medicinal and edible plant indigenous to Southeast Asian countries. Although previous studies suggested that the high content of total phenolics in S. pinnata fruits leads to their antioxidant activity, there is no systematic study on its chemical constituents. Aim: To investigate chemical constituents of S. pinnata fruit extract, which will benefit to the utilization of S. pinna Read More

Introduction: Cyanthillium cinereum has long been used in Thai traditional medicine. However, the standard information of C. cinereum raw material has not been established. Objective: This study aimed to present the standard information of C. cinereum raw material. Material and methods: The microscopic and macroscopic characteristics, the physicochemical analysis, and assays for bioactive contents of 24 sampl Read More

Background & Objective: Barley is widely used as a major staple of human food and animal feed. Several antioxidant phenols are found in barely, which have scavenging properties. The present study aimed to assess the protective effects of barley seed against the oxidative damage of brain tissues in a scopolamine-induced memory impairment model. Materials and Methods: In total, 32 male albino rats (mean weight: 250±1 Read More

Artocarpus heterophyllus has been used as a folk medicine. This plant contained a wide range of flavonoid compounds and possessed several pharmacological properties including anticancer properties. Chemotherapeutic agent is a major option for cancer treatment. However, it may lead to tumor relapse. Therefore, it needs to discover an alternative to reduce this limitation using natural products. Objective: This study wa Read More