Natural Products Journal, The - Volume 11, Issue 4, 2021

Channa striata (also known as Channa striatus) is an air-breathing freshwater snakehead fish that is well known in the Asian region for its medicinal properties, particularly in wound healing. It is recognised as a traditional medicine (TM), which can be served as alternative treatment method. With the advancement of technology, researchers have made a lot of progress in characterising the biomolecules of this fish. Various types o Read More

Epimedium sp. is a famous plant as sexual enhancer. In Chinese Pharmacopeia, Five species of Epimedium brevicornum, E. sagittatum, E. pubescens, E. koreanum, and E. wushanense were recorded as Epimedium Herba (Yin Yang Huo). The aim of this review article was to evaluate the potential efficacy of E. brevicornum as a remedy for sexual dysfunction and infertility. For preparing of this manuscript, we searched in a Read More

(±)-Indolizidine 209D is one of the alkaloids isolated from the skin secretions of certain neotropical frogs and exhibit a range of pharmacological properties, including blocking neuromuscular transmission. Therefore, the synthesis of indolizidine 209D and more complex derivatives, have been the subject of several publications. The preparation pathways of indolizidine 209D and its derivatives are the subject of this review. In thi Read More

Gloriosa superba: L. (G. superba) is a perennial creeper and climbs up to 5-7 meters. It belongs to the Liliaceae family and is native to Africa and South-East Asia. It is also categorized as an endangered plant which may be due to its extensive use. Objective: The objective of the present review is to explore anticancer potential with other pharmacological activities of G. superba and its active constituents. G. superba has been re Read More

Parasitic worm infections are a major health issue around the world, which cause numerous physiological damages in the patient's infected organ(s). The aim of this review was to investigate the anthelmintic properties of various medicinal plants. In this systematic review, all Randomized Controlled Trials (RCTs), quasi-experimental and experimental studies examining the anthelmintic effects were retrieved from databases, Read More

Background: The study aimed to compare the antimicrobial activity and cytotoxicity of saponin extracted from six sea-cucumber species, licorice, and ginseng to determine the most potent one. Methods: Antimicrobial activity assessed by well diffusion and agar dilution methods. The inhibitory effects of the tested extracts on cell growth of Liver (HePG-2) and breast (MCF-7) cell lines assessed by MTT [3- (4, 5- dimethyl thiazol-2y Read More

Background: Metribuzin (Mtz), a pesticide often used on vegetable crops to control broadleaf and grassy weed species has shown significant toxicity to humans and animals. Many plant extracts have been reported to have multiple biological properties. Ephedra alata extract might be useful in preventing and protecting the population from getting affected by metribuzin toxicity. Objective: The current study evaluates the protect Read More

Background: Diabetic Nephropathy (DN), a microvascular complication of diabetes has been a significant health issue globally. However, theaflavin enriched black tea extract (BTE-TF) could restrain DN. Objective: The main objective of this exploration was to elucidate the effect of BTE-TF on DN, though the underlying mechanism remains unclear and requires further investigation. Methods: The tea leaves were fermented to get bl Read More

Background: The use of red propolis has antimicrobial, anti-inflammatory, antioxidant activity results, and provides local conditions that optimize events involved in the healing process, accelerating tissue repair. Objective: To evaluate the chemical composition, antioxidant activity, cytotoxic effects, and healing potential of Red Propolis Hydroethanolic Extract (RPHE) on the surgical wounds of cats submitted ovarisalpingohister Read More

Background: Orthosiphon aristatus is a popular medicinal herb because of its pharmacological significance. Therefore, a lot of products formulated from the plant extract are available in the market. However, many phytochemicals in the plant extract are still remained to be unknown. Objective: The objective of this study was to profile phytochemicals from the plant extracts prepared using water and ethanol in a reflux system fo Read More

Background: Sunset yellow is a commonly used synthetic food additive in various food beverages. Over usage of this colorant induces the anxiogenic behaviour in mice through oxidative stress. Vernonia cinerea reverses anxiogenic behaviour by counteracting oxidative stress. Objective: The study was designed to screen the protective effect of Vernonia cinerea extract against sunset yellow induced anxiogenic Read More

Objective: Diabetic Neuropathic Pain (DNP) is a common complication in both types of diabetes, which does not respond well to common pain medications. Asafoetida, an oleo-gum-resin extracted from Ferula asafoetida, is used as an analgesic, sedative, and antispasmodic in Iranian traditional medicine. Hence, the present study aimed to investigate the anti-neuropathic pain effects of asafoetida in streptozotocin-indu Read More

Background: Long-term administration of valproic acid (VPA) is known to promote renal tubular injury mediated by an increase in renal oxidative stress. Recent evidence indicates that natural antioxidants are alternative to attenuate oxidative stress and kidney damage. Objective: This study was performed to investigate the protective effects of n-butanol extract of Rhanterium suaveolens, vitamin E (Vit E), and vitamin C (Vit Read More

Background: C. delpyi, C. decalvatus and C. caudatus are in the Euphorbiaceae family. The aerial parts, such as twigs, leaves and barks of these plants are used as traditional medicine such as anti-inflammatory, cytotoxicity, and antifungal properties. Objectives: The aims of this work were 1) to study the chemical composition of C. delpyi, C. decalvatus, and C. caudatus 2) to test the antibacterial, anti-HIV-1 RT, and cytotoxicity Read More

Background: The production of insecticidal proteins is one of the greatest vital direct defense responses in plants against the attack by phytophagous insects. One particular class of the entomotoxic proteins present in many plant species is lectins that is used against a wide range of important insects. Aim: The insecticidal activity of two lectins from seeds of white kidney bean (Phaseolus vulgaris) and soybean (Glycine Read More

Background: Plant derived compounds, naringenin and ellagic acid might interfere in MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) assay in the form of reducing the tetrazolium salt in the absence of cells. Objective: Effect of naringenin and ellagic acid in MTT assay. Methods: MTT assay has been performed in different conditions like, varying the concentration of phytocompounds, incubation time, an Read More