Mini-Reviews in Organic Chemistry - Volume 20, Issue 4, 2023

Oxadiazole is a five-membered aromatic heterocyclic ring having two nitrogen and one oxygen atom. Various isomeric forms have been reported for oxadiazole, such as 1,3,4-oxadiazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, etc. Currently, a considerable population worldwide is facing several mental problems due to a competitive lifestyle. The present status of available medicines do not promise complete cure without any adv Read More

Simple heterocyclic moieties are quite famous in synthetic organic chemistry due to their bioavailability, ease of laboratory synthesis, and variety of applications in multidisciplinary fields. Benzimidazole is an N-containing benzo-fused chemical compound with the formula C7H6N2 and belongs to the family of heterocyclic aromatic organic compounds. It is a potent bioactive molecule with prominent therapeutic activities and has b Read More

2-pyridones represents ubiquitous scaffolds often present in both natural products and pharmaceutical compounds. Due to their wide applications in medicinal chemistry, it is not surprising that the synthesis of 2-pyridone derivatives has attracted organic chemists for many years. This mini review focuses on the recent development in the multi-component synthesis of 2-pyridones for the period 2011 to 2021, particularly tho Read More

p-Tosylmethyl isocyanide (TosMIC) and its derivatives represent an important class of polyfunctional reagents, making them privileged “building blocks” in the targeted organic synthesis to design a plethora of heterocycles as well as natural products. This review summarizes and highlights the synthetic potential of p-tosylmethyl isocyanide and its derivatives in the reaction with various aldehydes to afford valuable heterocyc Read More

The review summarizes information regarding the industrial use of 3- and 4-amino-1,2,4- triazoles, the basic raw material for the industry of fine organic synthesis. A description of the existing production methods for the synthesis of 3- and 4-amino-1,2,4-triazoles under laboratory conditions is provided. Three main areas of use of these amines and their derivatives have been identified: Agriculture, medicine, high-energy substa Read More

Efficient translation of CO2 into value-added compounds is a fascinating topic in green chemistry. The effective conversion of CO2 into useful chemicals and materials helps civilization flourish in the long run. Carbon dioxide has shown tremendous applications by replacing dangerous chemicals like phosgene, isocyanates, or carbon monoxide, resulting in more environment-friendly operations. This article is an overvie Read More

Functionalized polysubstituted quinoxalines have been widely reported to possess appealing biological activities of great pharmaceutical importance, which drew researchers into exploring promising synthetic protocols. On top of that, prospects on green chemistry are driving research paradigms into more cost-effective, facile, environmental-friendly, sustainable, and scalable approaches. This paper reviews th Read More