Mini-Reviews in Organic Chemistry - Volume 20, Issue 8, 2023

The extension of carbon chains, known as homologation, is one of the most fundamental operations of organic synthesis. One and two-carbon homologation reactions are of immense importance because they can be used for synthesizing members of a homologous series by iterative operations. Homologation reactions produce higher analogues of the same functional group, whereas homologation- functional group in Read More

Malaria is a parasitic infection caused by Plasmodium parasites that are transmitted to humans through the bite of infected Anopheles mosquitoes. Malaria continues to contribute unacceptably high rates of sickness and death. Natural product compounds have long been recognized as one of valuable natural remedy resources with promising structural motif pools for the development of first-line drugs. Resistance to conventio Read More

Among the several heterocyclic compounds containing aza- and oxa-heterocycles are predominant due to their abundant biological importance. The nanoparticles have demonstrated excellent catalytic activity under optimum conditions with higher reusability or recyclability and higher yields of synthetic heterocyclic targets. Previously we reviewed the synthesis of aza- and oxa-heterocycles catalyzed by metal nanoparticles ( Read More

Background: Acronychia is a genus of medicinal plants that were used traditionally to treat various ailments such as cough, asthma, sores, ulcers, itchy skin, fever, and rheumatism. Acronychia plants have a wide range of distribution, but they are mostly native to India, Siri Lanka, Australia, and Indochina since the 1950s Acronychia plants have been extensively used in phytochemical research and pharmacological examinations. Read More

Among various emerging organofluorine molecules, gem-difluorovinyl sulfonates are attractive building blocks and less used in organic reactions. This review article is concerned with recent advances in organic reactions using gem-difluorovinyl sulfonates in recent years. We discussed the reactions of gem-difluorovinyl sulfonates with aldehydes, amines, imines, amides, boronic acids, aryl halides, etc. or addition, reduction, Read More