Mini-Reviews in Organic Chemistry - Volume 20, Issue 7, 2023

Neem tree (Azadirachta indica), native to the Indian subcontinent, is known as a versatile plant, a rich source of bioactive compounds such as azadirachtin, nimonol, nimocinol, nimocinolide, gallic acid, gallocatechin, epicatechin, azadiradione, nimbin, salannin, epoxyazadiradione, etc. The isolated phytochemicals from neem, among others, are more than 300. The present work details the techniques for extracting compou Read More

Organic dye-based nanoparticles (ODNPs) are fabricated with desired morphologies using laser ablation, reprecipitation, ion association, and self-assembly methods. Primitively, this review introduces the theory of the molecular origins of dye aggregation, manifestations of the formations of monomer to J-dimer, H-dimer, and oblique dimer (mixed J and H dimer) in ODNPs. Although, organic dye nanoparticles have better basic Read More

1-Deoxysphingolipids are a class of sphingolipids which lacks the primary hydroxyl group (C1-OH). Hence, it does not get converted/degraded to complex corresponding products like sphingosine- 1-phosphate (SIP), a pro-mitotic. Enigmol, an orally bioavailable 1-deoxyphingolipid has shown potential against various different types of cancer cells along with impressive cytotoxic/ antiproliferative properties. Due to its unique str Read More

Extensive research has been documented in the last few decades on the utilization of near IR, visible and UV light in organic chemical transformations. In this brief review, we provide an overview of the most noteworthy achievements in the area of photocatalytic Suzuki coupling reactions by palladium (Pd)-based catalytic systems. The works on different types of Pd-based photocatalysts for Suzuki coupling reactio Read More

This review discussed the synthetic applications of propiolic acids in the preparation of diverse N-heterocycles. 3~9-membered rings like azirines, β-lactams, oxazolidin-2-ones, 2-oxindoles, indoles, isoindolin-1-ones, imidazo[1,2-a]pyridines, triazoles, 2-pyridones, 2-quinolones, 1,4- benzothiazines, thiazinones, spiroindolines, etc. could be constructed via radical addition, fourcomponent Ugi reactions, 1,3-dipolar cycloadditions, or Di Read More

Based on the type of metal or non-metal catalyst used, the authors of this paper have clearly highlighted the different applications of air-stable, commercially viable, and environmentally friendly polymethylhydrosiloxane (PMHS) in organic synthesis or other allied reactions. The importance of PMHS was emphasised for the particular organic transformation's success. In addition to its wellknown use as a reducing agent, it has al Read More

Nitrogen based heterocycles display an impressive repertoire of biological activities, including antioxidant, antimicrobial, anti-tuberculosis, analgesic, anti-inflammatory, anti-viral, anti-HIV, anticancer, anti-helminthic, and other pharmacological activities. Numerous novel nitrogen-based heterocycles have been synthesized, which showed various physiological properties, and their application in medicinal chemistry is ever- Read More