Mini-Reviews in Organic Chemistry - Volume 20, Issue 1, 2023

5-Arylidene-2,4-thiazolidinedione (5-A-TZD) is an emerging precursor molecule in medicinal chemistry for discovering multifunctional therapeutic agents. For synthesizing this precursor molecule, Knoevenagel Condensation (KC) is one of the most excellent tools in modern organic chemistry. The 5-A-TZD framework has a variety of therapeutic functions such as antidiabetic, anticancer, antimicrobial, and anti-inflammatory. As Read More

Ionic liquid-promoted one-pot synthetic methodologies have emerged as a frontier for the facile access of diverse heterocycles. Owing to the high adaptability of ionic liquids (ILs), the design of functionalized ILs with desired specific and attuned properties, ideally satisfying the one-pot syntheses, are of great importance and endeavor. In particular, with the addressed drawbacks related to the use of ionic liquids as a ho Read More

Heterocyclic compounds have specific structural peculiarities, imparting immense applications in various fields. This study has explored the medicinal importance of a captive heterocyclic compound, 1H-Indole-2,3dione, commonly known as isatin. The flexibility in the structure of isatin makes it more innovative to have applications in the biological and analytical fields. In this minireview, we have discussed Schiff bases of Read More

Carbon Nanotubes (CNTs) possess a unique one-dimensional molecular geometry with a large surface area. Recently, CNTs have become a thrust area of research as they play a crucial role in molecular engineering due to their excellent mechanical, electrical, and thermal properties. CNTs have a wide range of applications in various fields due to their unique properties. The Multiple Walled Carbon Nanotubes (MWCNTs) are t Read More

Background: Vilsmeier-Haack formylation of N-arylacetamides and used them as a key intermediate for preparation of 2-(piperidin-1-yl) and/ or 2-(morpholin-1-yl) quinoline-3- carbaldehydes. these used as precursors for the synthesis of 2-(piperidin-1-yl) and/ or 2-(morpholin- 1-yl) quinoline derivatives through the reaction with active methyl and/ or methylene component, Claisen-Schmidt condensation, one-pot multicompon Read More