Mini-Reviews in Organic Chemistry - Volume 20, Issue 6, 2023

This mini-review summarizes the methods available for the synthesis of transition metalsulfur complexes, which have been used as models of metalloprotein active sites, desulfurization catalysts, and organometallic functional materials. All the methods use silicon-sulfur compounds as starting materials, exploiting the selective cleavage of Si-S bond and the subsequent incorporation of sulfur fragments into the metal co Read More

Prins reaction is a very useful and important reaction in the field of synthetic organic chemistry. Prins cyclization is one of the greatest significant synthetic approaches in the total synthesis of various natural compounds especially pyran and furan units. The addition of aldehydes to olefinic compounds utilizing acid catalyst has become important for the industry. Aldehydes and alkenes to give different products depending on Read More

Pathogenic microorganisms cause serious and lethal infectious diseases. Numerous antimicrobial agents have been developed during the last few decades to treat these infectious diseases, but these are still expanding worldwide. Moreover, microorganisms are developing resistance against commercially available medicines. So, antimicrobial resistance is expanding as the most serious health threat particularly in developing Read More

Formyl-selective deuteration of aldehydes is one of the important synthetic methods in the field of medicinal chemistry. Aldehyde-d is often used as an important building block for pharmaceutical and drug synthesis due to its versatile reactivity and applicability. Due to the recent interest and development in the use of deuterated pharma drugs, there is an urgent need for simple and practical synthetic methods that are effecti Read More

Uranium, the primary fuel source for nuclear power reactors, is one of the most crucial components in new energy production. Currently, uranium is mainly mined from land ore, which will be exhausted within 200 years. As the world's largest uranium reservoir, the ocean is an ideal source for people to obtain these industrial resources. However, the low concentration of uranium (typically about 3.3 ug/L) in seawater poses a gr Read More

Quinoline and pyrimidine are well-known moieties, which appear in various natural and synthetic products. Furthermore, quinoline-pyrimidine-inspired hybrids are known to have several biological properties. In addition, many pyrimido[4,5-b]quinolinone ring systems, specifically concerning medicinal chemistry, have been reported over the past decade. This review depicts the synthesis of pyrimido[4, 5-b] quinolones (PyQs4, Read More