Current Pharmaceutical Design - Volume 27, Issue 22, 2021

Datura metel (Solanaceae) which is commonly known as thorn’s apple, Indian apple or devil’s trumpet isan annual herb of temperate zones which is distributed all over the world. D. metel belongs to the family solanaceae. From a longer period of time (37 A.D), species of this family had therapeutic uses. This article is based on the review of different scientific backgrounds and studies regarding the traditional uses, phytoc Read More

Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide, directly related to the progressive increase in body weight and obesity. The accumulation of lipids in patients with NAFLD contributes to the development of insulin resistance, inflammatory response and oxidative stress in hepatocytes and alteration of the circulating lipid and glycaemic profile. Howe Read More

Background: Plants have been used to treat health disorders and prevent diseases since antiquity in all civilizations including the Indian and Chinse. Giloy (Tinospora cordifolia L.) is one of the most important medicinal plants in Indian folk medicine and is commonly known as the “Heart-leaved Moonseed” or “Guduchi”. Giloy is a perennial shrubby creeper of the Menispermaceae family. It is native to the tropical areas of India, Sr Read More

There is increasing interest in evaluating anti-inflammatory activities of plant substances such as extracts and flavonoid rich fractions. A promising source of new medicinal drugs may be species from the Passifloraceae family. The most interesting group of principal chemical substances in Passiflora species are polyphenolic compounds, including flavonoids (quercetin, rutin, apigenin, luteolin, chrysin, and C-glycosylflavones i Read More

Marine fungi with their successful pharmacological effects were considered to be the treasure of ocean medicines concerning the striking ability of their secondary metabolites. Literature over literature has been published on fungi derived bioactive molecules to probe its therapeutic potential. Marine fungi have an implicit to cede future medicines against life-threatening diseases, such as cancer and several emerging inflamma Read More

Mentha spp. are aromatic plants and have been used in the medical, cosmetics, and food industries. These plants have been used as a traditional herbal medicine for various types of diseases. Mentha aquatica L. (water mint) is a perennial plant used as a wild vegetable and a culinary herb. As its name suggests, it grows in the shallow margins and channels of streams, rivers, wet meadows, etc. It has been used as a tonic plant, Read More

Natural products have served as a limitless reservoir of bioactive scaffolds for drug discovery against several disorders. Furanodiene is a bioactive natural product isolated from several plants of genus Curcuma. Its therapeutic potential against cancer, inflammation, and angiogenesis has been well-documented. The current review is an update about the natural sources and anti-cancer action mechanism of furanodiene. Furano Read More

Alzheimer's disease (AD) is an age-related progressive neurodegenerative disorder that significantly affects cognitive functions in a way that causes loss of memory, thinking, and behavior. Multiple studies revealed that neuroinflammation associated with AD is linked with the amyloid-beta deposition in the brain. Elevated levels of expression of cytokines, microglial activation, nuclear factor kappa B, and reactive oxygen spe Read More

The family Zygophyllaceae has almost 22 genera and more than 250 species. Fagonia is an important genus of the family Zygophyllaceae. This genus comprises abundant species, which grows in different phytogeographical regions of the world. These species grow in different environmental conditions. Fagonia indica belongs to Zygophyllaceae. It is commonly known as Dhamasa, Dhamana, Sachi booti and Shoka’a and is fou Read More