- Home
- A-Z Publications
- Current Pharmaceutical Design
- Previous Issues
- Volume 19, Issue 11, 2013
Current Pharmaceutical Design - Volume 19, Issue 11, 2013
Volume 19, Issue 11, 2013
-
-
Advances in Clinical Study of Curcumin
Authors: Chunfen Yang, Xun Su, Anchang Liu, Lin Zhang, Aihua Yu, Yanwei Xi and Guangxi ZhaiCurcumin has been estimated as a potential agent for many diseases and attracted great attention owing to its various pharmacological activities, including anti-cancer, and anti-inflammatory. Now curcumin is being applied to a number of patients with breast cancer, rheumatoid arthritis, Alzheimer's disease, colorectal cancer, psoriatic, etc. Several clinical trials have stated that curcumin is safe enough and effective. The o Read More
-
-
-
Recent Progress in Studying Curcumin and its Nano-preparations for Cancer Therapy
Authors: Jieying Liu, Siyuan Chen, Li Lv, Lei Song, Shengrong Guo and Shengtang HuangA hydrophobic polyphenol compound extracted from turmeric, curcumin has been widely utilized as traditional medicines for centuries in China and India. Over the last decades, because of its low toxicity, extensive studies have been focused on its physicochemical properties and pharmacological activities on various diseases, such as cancer, cardio-vascular disease, inflammatory bowel, wound healing, Alzheimer' Read More
-
-
-
Curcumin Nanomedicine: A Road to Cancer Therapeutics
Authors: Murali M. Yallapu, Meena Jaggi and Subhash C. ChauhanCancer is the second leading cause of death in the United States. Conventional therapies cause widespread systemic toxicity and lead to serious side effects which prohibit their long term use. Additionally, in many circumstances tumor resistance and recurrence is commonly observed. Therefore, there is an urgent need to identify suitable anticancer therapies that are highly precise with minimal side effects. Curcumin is Read More
-
-
-
The Clinical Applications of Curcumin: Current State and the Future
Authors: Xia Fan, Chun Zhang, Dong-bo Liu, Jun Yan and Hua-ping LiangCurcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as antioxidant activity, inducing cell apoptosis, inhibiting cell proliferation, anti-cell adhesion and motility, anti-angiogenesis and anti-microbe properties. Based on these functions, curcumin has been used in clinical trials on various inflammato Read More
-
-
-
A Review of Therapeutic Effects of Curcumin
Authors: Ali Noorafshan and Soheil Ashkani-EsfahaniThere is a growing interest in herbal medicine. Scientific studies have demonstrated the beneficial pharmacological effects of curcumin. Curcumin is a bright yellow spice, derived from the rhizome of Curcuma longa Linn. It has been proven that curcumin is a highly pleiotropic molecule which can be a modulator of intracellular signaling pathways that control cell growth, inflammation, and apoptosis. Curcumin might be a poten Read More
-
-
-
Perspectives on New Synthetic Curcumin Analogs and their Potential Anticancer Properties
Authors: Alok Vyas, Prasad Dandawate, Subhash Padhye, Aamir Ahmad and Fazlul SarkarCurcumin is the active component of dried rhizome of Curcuma longa, a perennial herb belonging to ginger family, cultivated extensively in south and southeastern tropical Asia. It is widely consumed in the Indian subcontinent, south Asia and Japan in traditional food recipes. Extensive research over last few decades has shown that curcumin is a potent anti-inflammatory agent with powerful therapeutic potential against a variety Read More
-
-
-
Delivery of Curcumin and Medicinal Effects of the Copper(II)-Curcumin Complexes
Authors: Mandy H. M. Leung, Takaaki Harada and Tak W. KeeCurcumin, a yellow pigment extracted from the rhizome of Curcuma longa, commonly known as turmeric, is the most active agent of this herbal medicine. The therapeutic activities of curcumin are exemplified not only by its enhancement in wound healing but also in the treatment of inflammation, cystic fibrosis, Alzheimer’s disease and cancer. There are two critical issues involving low aqueous stability and solubility t Read More
-
-
-
Curcumin: From Chemistry to Chemistry-Based Functions
Authors: Akiko Jitoe-Masuda, Aya Fujimoto and Toshiya MasudaCurcumin is a yellow pigment found in the spice turmeric and a main functional constituent of the rhizomes of Curcuma longa. The multi-functionality of curcumin has recently attracted much attention in various fields, including food, medicinal, and clinical industries. Three major curcuminoids, curcumin, demethoxycurcumin, and bis-demethoxycurcumin, are distributed in not only Curcuma, but also the Zingiber s Read More
-
-
-
Chemical and Structural Features Influencing the Biological Activity of Curcumin
More LessCurcumin, a polyphenolic natural product, exhibits therapeutic activity against a number of diseases, attributed mainly to its chemical structure and unique physical, chemical, and biological properties. It is a diferuloyl methane molecule [1,7-bis (4-hydroxy-3- methoxyphenyl)-1,6-heptadiene-3,5-dione)] containing two ferulic acid residues joined by a methylene bridge. It has three important functionalities: an aromatic o-methoxy Read More
-
-
-
Antioxidant and Antiinflammatory Activities of Curcumin on Diabetes Mellitus and its Complications
More LessDiabetes mellitus (DM) has reached pandemic status and shows no signs of abatement. It can severely impair people's quality of life and affects patients all over the world. Since it is a serious, chronic metabolic disease, it can bring about many kinds of complications, which can in turn increase mortality. In recent decades, more and more studies have shown that oxidative stress and inflammatory reactions play critical Read More
-
-
-
Promising Curcumin-based Drug Design: Mono-carbonyl Analogues of Curcumin (MACs)
Authors: Chengguang Zhao, Zhiguo Liu and Guang LiangCurcumin exhibits a surprisingly wide range of chemo-preventive and chemo-therapeutic activities. Curcumin has undergone more than 40 clinical trials for the treatment of inflammatory diseases and various human cancers. However, phase I/II clinical trials have shown that curcumin exhibit poor bioavailability in humans. Major reasons resulting in the low plasma and tissue levels of curcumin appear to be its poor absorption, Read More
-
Volumes & issues
-
Volume 31 (2025)
-
Volume 30 (2024)
-
Volume 29 (2023)
-
Volume 28 (2022)
-
Volume 27 (2021)
-
Volume 26 (2020)
-
Volume 25 (2019)
-
Volume 24 (2018)
-
Volume 23 (2017)
-
Volume 22 (2016)
-
Volume 21 (2015)
-
Volume 20 (2014)
-
Volume 19 (2013)
- Issue 42
- Issue 41
- Issue 40
- Issue 39
- Issue 38
- Issue 37
- Issue 36
- Issue 35
- Issue 34
- Issue 33
- Issue 32
- Issue 31
- Issue 30
- Issue 29
- Issue 27
- Issue 26
- Issue 25
- Issue 24
- Issue 23
- Issue 22
- Issue 21
- Issue 20
- Issue 19
- Issue 18
- Issue 17
- Issue 16
- Issue 15
- Issue 28
- Issue 14
- Issue 13
- Issue 12
- Issue 11
- Issue 10
- Issue 9
- Issue 8
- Issue 7
- Issue 6
- Issue 5
- Issue 4
- Issue 3
- Issue 2
- Issue 1
-
Volume 18 (2012)
-
Volume 17 (2011)
-
Volume 16 (2010)
-
Volume 15 (2009)
-
Volume 14 (2008)
-
Volume 13 (2007)
-
Volume 12 (2006)
-
Volume 11 (2005)
-
Volume 10 (2004)
-
Volume 9 (2003)
-
Volume 8 (2002)
-
Volume 7 (2001)
-
Volume 6 (2000)
Most Read This Month
Article
content/journals/cpd
Journal
10
5
false
en
