Coronaviruses - Volume 6, Issue 1, 2025

IntroductionCOVID-19 is a global pandemic that has caused significant mortality. The disease severity varies among individuals, and the factors influencing its course remain unclear. This study aimed to investigate the influence of biochemical parameters and familial data on COVID-19 outcomes.MethodsA retrospective analysis of 122 COVID-19 patients was conducted. Patients were categorized into two groups: outpati Read More

Hypocrellin A and Pheophorbide a are well-known organic chemicals that may be contained in herbal products. They can act as photosensitizers and have a strong photodynamic effect on bacteria. In any case, are these photosensitizers appropriate for photodynamic treatment against the SARS-CoV-2 infection? The principles of photodynamic therapy are the same regardless of the target. It causes selective cytotoxicity at t Read More

AimThis study aimed to determine the factors related to hospitalization associated with COVID-19.MethodsA total of 1000 patients with confirmed COVID-19 by positive PCR test participated in this study. They were randomly selected from positive test patients during this time. They or their first-degree relatives were contacted over the phone and were asked the questions of the checklist regarding socio-demographics and f Read More

BackgroundCoronaviruses are the genetic series of RNA viruses that infect both organisms mammals and birds. Different varieties of illnesses shown in humans as well as in birds are the most common causes ranging from minor to fatal. Common colds which are included in mild and SARS, MERS, and COVID-19 are caused by fatal. After cell entry, the release of RNA into the cytoplasm occurs, which translates viral proteins f Read More

The COVID-19 virus has killed more than 6.3 million people worldwide. The misuse of antibiotics increased during epidemics, leading to the spread of MDRs. Although antibiotic use is increasing in both developed and developing countries, the utility level and abuse are higher in developing countries. This could have negative consequences for the vaccine, especially considering that many developing countries reported the e Read More

BackgroundThe spike glycoprotein of SARS-CoV-2, via its S1-subunit, binds with host angiotensin-converting enzyme 2 (ACE-2) receptors, and its S2-subunit mediates the fusion of the virus to the host cell. The entry of SARS-CoV-2 inside the host cell can be prevented by inhibition of the receptor binding domain (RBD) of S1-subunit of the spike. Anacyclus pyrethrum, a native herb of Algeria, Spain and Morocco has antidepressant, Read More

BackgroundComputerized Tomography (CT) was extensively used in the COVID-19 era to confirm the diagnosis and follow the patient's response. The vaccine was rapidly introduced to break the disease chain of infection. The current study primarily aimed to examine the relationship between vaccination status and pulmonary CT findings. Moreover, it also aimed to validate the role of CT scan along with other patient criteria in Read More

BackgroundThe ongoing 2019 novel coronavirus pneumonia pandemic continues to pose a serious threat to public health and safety. In response, numerous specific anti-SARS-CoV-2 drugs have been urgently approved for use. Azvudine has been recommended as a priority treatment for COVID-19 patients, but its efficacy and safety in elderly patients remain unexplored.MethodsIn this retrospective, single-center, observat Read More

Background and ObjectiveThinqure20 is a polyherbal, reverse-pharmacology-based formulation that contains Piper longum, Piper nigrum, Zingiber officinale, and rock salt as active ingredients. It is designed to work as an effective antiviral agent and also as a preventive measure against SARS-CoV-2. Clinical and non-clinical studies have established significant safety efficacy and tolerability of Thinqure20 formulation in the treat Read More

IntroductionIt has been four years since the onset of the COVID-19 pandemic. In addition to medical professionals, medical students have also been at the forefront of the fight against this pandemic and, like them, have been highly susceptible to the virus. The aim of this study was to evaluate the level of knowledge of Iranian medical students about COVID-19, preventive behaviors, and their perception of risk in the second yea Read More

After the COVID-19 pandemic, the world has been vulnerable due to another virus called monkeypox. Monkeypox is a very uncommon zoonotic infectious condition that occurs in both human and non-human primates with similar clinical characteristics as smallpox along with remarkable epidemic potential because of the increasing existence of human outbursts in recent scenarios. The increasing number of cases of this v Read More

ObjectiveSome pregnancies are affected by liver dysfunction, and differentiating them from possible liver dysfunction caused by COVID-19 in pregnancy will lead to a better therapeutic approach and management.AimsThe current study was conducted with the aim of investigating changes in liver function tests (LFTs) in pregnant women with mild and severe COVID-19.MethodsIn this retrospective observational study, 130 pr Read More