Current Organocatalysis - Volume 11, Issue 4, 2024

Introduction Dihydropyrimidinone (DHPM) is a very useful moiety with a wide range of applications. Synthesis of this moiety with environmentally friendly methods is the demand of the era. Methods In recent research, the optimisation of curd as a biocatalyst has been studied. It has been reported that it can be used directly in the multicomponent Biginelli synthesis of ethyl 6-methyl-2-oxo-4-benzyl-1,2,3,4-tetrahydropyrimi Read More

Nanoparticles have emerged as highly promising catalysts due to their unique physical and chemical properties arising from their small size and high surface area–to–volume ratio. This review delves into the diverse applications of nanoparticles as catalysts in various chemical reactions. A key advantage lies in their substantial surface area–to–volume ratio, facilitation, enhanced accessibility of reactants, and heightened interac Read More

Background Assessing the efficacy of remdesivir for COVID-19 infection holds historical significance. Understanding its effectiveness from previous pandemic instances can enable us to gain insights into its efficacy, informing our strategies for responding to future outbreaks or variants. Objective Gaining an insight into the historical efficacy of remdesivir can offer valuable data for evaluating the advancement of COVID-1 Read More

TiCl4 is a widely utilized reagent in organic synthesis, often functioning through Lewis’s acid-promoted transformations. This review explores the potential for TiCl4 to catalyse various examples, adhering to the classic catalyst definition and allowing for the use of sub-stoichiometric quantities of the catalyst relative to the substrate. The use of metal catalysts in organic synthesis has witnessed a surge in interest due to their abil Read More

The main emphasis of green chemistry is to reduce environmental pollution. Its main goal is to adopt a cost-effective and harmless strategy for human health and the environment. The green synthetic routes have succeeded in adopting solvent-free conditions as an effective tool for sustainability. Heterocycles are organic compounds that are widely distributed by nature. Many of them possess medicinal and pharmac Read More

Introduction In this study, the identification and quantification of biogenic amines in 45 commonly consumed food samples in Saudi Arabia were carried out. The enzymes responsible for producing these biogenic amines include spermidine (SPD), putrescine (PUT), tryptamine (TRP), tyramine (TYR), and histamine (HIS), which are synthesized through organo-catalytic pathways. Methods The diverse range of samples analyzed e Read More

Background MCRs are one of the most significant tools in the synthesis of organic compounds. MCR is a rapid chemical technique that uses three or more reactants to produce products that sustain all structural and substructural properties of the initial components. MCRs are useful in all fields of synthetic chemistry because of their rapid rate of reaction, simple procedure and excellent yields. We reported an efficient and environ Read More

Background Knoevenagel condensation is an important C-C bond formation reaction catalyzed by various homogeneous and heterogeneous acid-base catalysts. Methods The present work describes the eco-friendly preparation of magnetic nanoparticles Fe3O4 (MNPs) and its functionalization to Fe3O4@SiO2@SO3H. The prepared MNPs and their functionalized materials were fully characterized by FT-IR, XRD, FE-SEM, HR-TEM, Read More