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Volume 2, Issue 1
  • ISSN: 2210-299X
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Abstract

Background

Ovarian cancer is the most fatal gynecological cancer, with the highest death rate because of its late diagnosis and recurrence. Owing to the inherent drawbacks of conventionally available approaches for ovarian cancer treatment, alternative strategies need to be developed. Recently, nanotechnology-based drug delivery vehicles (polymer, liposome, dendrimers, .) have been extensively used in cancer therapy, especially for ovarian cancer. Among various nanoformulations, metal nanoparticle-based approaches are widely studied for ovarian cancer treatment as they offer several advantages, such as high therapeutic output, biocompatibility, non-toxicity, non-inflammatory effects, biodegradability, .

Objective

This review aimed to emphasize the advancement of metal-based nanoformulations for ovarían cancer therapy along with toxicological aspects.

Methods

The information was gathered from many search engines, such as SciFinder, PubMed, and ScienceDirect, to get coverage of suitable research and compile relevant data about metal nanoparticles for ovarian cancer treatment.

Results

Investigating metal nanoparticle-based therapies for the treatment of ovarian cancer provides a new direction for future studies.

Conclusion

This review highlights the anti-cancer activity of metal nanoformulations for ovarian cancer therapy, recent progress, challenges, and future perspectives in detail, along with the toxicological aspects.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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/content/journals/cis/10.2174/012210299X310916240801111606
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Metal Nanoparticles for Ovarian Cancer Therapy
Curr. Indian Sci. 2, e2210299X310916 (2024); https://doi.org/10.2174/012210299X310916240801111606
/content/journals/cis/10.2174/012210299X310916240801111606
/content/journals/cis/10.2174/012210299X310916240801111606
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  • Article Type:     Review Article
Keyword(s): Cancer therapeutics; Drug delivery; Metal nanoparticles; Nanotechnology; Ovarian cancer; Toxicity

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