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Volume 2, Issue 1
  • ISSN: 2210-299X
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Abstract

Fungi are widely acknowledged as one of the most diverse and ecologically significant organisms with substantial economic importance on Earth. Edible and medicinal mushrooms have been recognized by human societies since ancient times, serving not only as valuable sources of nourishment but also as medicinal agents. The primary objective of this study is to explore the fruiting bodies of edible mushrooms and assess their capacity to serve as reservoirs of bioactive metabolites with pharmaceutical potential. The extensive analysis conducted aimed to elucidate the significant potential of these medicinal mushrooms, comparable to that of plants, in producing valuable bioactive compounds, thereby positioning them as abundant reservoirs for pharmaceutical compounds.

Fungi produce many different bioactive compounds of different molecular weights, including lectins, lipids, peptidoglycans, phenols, polyketides, polysaccharides, proteins, polysaccharide-protein/peptide complexes, ribosomal and non-ribosomal peptides, steroids, terpenoids, and others. These compounds have more than 130 different therapeutic properties, such as analgesic, antimicrobial, antifungal, anti-inflammatory, anti-plaque, antiviral, cytotoxic, hepatoprotective, cholesterol-lowering, blood-sugar-lowering, blood-pressure-lowering, immune system, response system modulation, immune suppression, cell growth stimulation or regeneration, and more. Several bioactive polysaccharides or polysaccharide-protein complexes identified in these medicinal mushrooms seem to augment both innate and cell-mediated immune responses. Furthermore, these compounds display anti-tumor properties in both animal models and humans.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-07-24
2025-03-01

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/content/journals/cis/10.2174/012210299X285895240521042601
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Medicinal Value of Mushroom: A Deeper Insight
Curr. Indian Sci. 2, e2210299X285895 (2024); https://doi.org/10.2174/012210299X285895240521042601
/content/journals/cis/10.2174/012210299X285895240521042601
/content/journals/cis/10.2174/012210299X285895240521042601
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  • Article Type:     Review Article
Keyword(s): Bioactive compound; Fungi; Minerals; Mushroom; Pharmaceutical compound; Proteins

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