Current Chinese Chemistry - Volume 2, Issue 1, 2022

C-Methylation of organic substrates was accomplished with a number of methylating agents other than methane, methanol, and methyl metals. They include methyl halides (MeX, X = I, Br, Cl, F), methyl-containing halogenated reagents, methyl peroxides, dimethyl carbonate (DMC), dimethylsulfoxide (DMSO), N,N-dimethyl formamide (DMF), diazomethane, formate salts, trioxane, CO/H2, CO2/H2, and dimethyl ether ( Read More

Background: Detection of explosives (Nitroaromatic compounds) is one of the major issues faced in global security and, to date, remains a challenge even though some materials are developed for their detection. This study introduces the use of polyvinylpyrrolidone (PVP), a non-conjugated conducting polymer, as a potential fluorophore for sensing nitroaromatics. The stimuli-response of fluorescence of PVP on in Read More

Objective: A simple, rapid, precise and accurate RP-HPLC stability indicating method was developed and validated for the estimation of Febuxostat in bulk drug and marketed tablet formulation.Methods: The chromatographic separation was achieved on Agilent C18 (250 x 4.6 mm, 5 µm) using solvent 15 mM ammonium acetate buffer (pH 4.8) and acetonitrile (30:70 v/v) as a mobile phase at flow rate of 1 mL/min and ambient c Read More

Background: Cilnidipine and Metoprolol Succinate are antihypertensive agents used in the treatment of hypertension. Methods: A pharmacokinetic study of Cilnidipine and Metoprolol Succinate in rat plasma was carried out using the chromatographic method.Methods: The chromatographic method involved a reverse phase C18 column, using acetonitrile and pH 4.0 water in the ratio of 80:20 v/v as mobile phase, a flow rate Read More

Aims: To achieve catalytic performance for the oxidation of alcohols using Ruthenium(III) metal complexes as a catalyst.Background: Chitosan is a potential candidate, which enables the synthesis of transition metal complexes from its corresponding bidentate ligands.Objective: The chemical modification was performed on a chitosan molecule with suitable aldehydes.Methods: The oxidation of alcohols was performed using rut Read More

Background: COVID-19 (SARS-CoV-2 infection) has affected almost every region of the world. Presently, there is no defined line of treatment available for it. Triphala is already proven to have a safe biological window, which is well known for its antioxidant and immunomodulatory properties.Objective: The present work has been carried out to study Triphala's effectiveness in the treatment of COVID-19.Methods: Th Read More