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- Volume 18, Issue 1, 2024
Recent Advances in Inflammation & Allergy Drug Discovery - Volume 18, Issue 1, 2024
Volume 18, Issue 1, 2024
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Insights into Prospects of Novel NSAID Prodrugs in the Management of Gastrointestinal Toxicity: A Perspective Review
Authors: Rajat Goyal, Sumeet Gupta, Prabodh Sharma and Manu SharmaNon-steroidal anti-inflammatory drugs (NSAIDs) have a long history in the healthcare system due to their therapeutic potential. These NSAIDs cause ulcerogenicity, stomach pains, gastrointestinal hemorrhage, mucosa bleeding, and pancreatitis when used moderately and consistently. With researchers, managing the aforementioned adverse effects therapeutically is getting increasingly difficult. One method for creating NSA Read More
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Modulation of the Immune System Mechanisms using Probiotic Bacteria in Allergic Diseases: Focus on Allergic Retinitis and Food Allergies
Allergic illnesses occur when an organism's immune system is excessively responsive to certain antigens, such as those that are presented in the environment. Some people suffer from a wide range of immune system-related illnesses including allergic rhinitis, asthma, food allergies, hay fever, and even anaphylaxis. Immunotherapy and medications are frequently used to treat allergic disorders. The use of probiotics in ba Read More
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From Traditional Medicine to Advanced Therapeutics: The Renaissance of Phyto-nano Interventions in Psoriasis
Authors: Rajneesh Semele, Sonam Grewal, Manish Kumar Jeengar, Thakur G. Singh and Rajan SwamiPsoriasis is an autoimmune systemic chronic inflammatory disease that exhibits characteristic detrimental effects on the skin, often leading to infections or comorbid conditions. The multifaceted nature of psoriasis has made it very challenging to treat, especially with current chemotherapy options. Therefore, it is essential to consider phytoconstituents as novel alternatives. However, despite demonstrating higher anti-inflam Read More
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Decrypting the Pathological Pathways in IgA Nephropathy
Authors: Rajiv Jash, Kousik Maparu, Sanket Seksaria and Saptarshi DasIgAN is the most common form of glomerulonephritis affecting 2000000 people annually. The disease ultimately progresses to chronic renal failure and ESRD. In this article, we focused on a comprehensive understanding of the pathogenesis of the disease and thus identifying different target proteins that could be essential in therapeutic approaches in the management of the disease. Aberrantly glycosylated IgA1 produced by Read More
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Antibacterial and Antimalarial Therapeutic Agents: A Patent Perspective
Authors: Hai-Long Zhang and Yongxia LiBackground: Antibacterial and antimalarial drugs play a critical role in combating infectious diseases. It is a continuous work to develop new types of antibacterial and antimalarial drugs. Objective: To better understand current landscape and association of antibacterial and antimalarial agents, the European patent analysis was performed. Methods: Antibacterial and antimalarial agents were analyzed by patent analysis. Patent d Read More
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Olfactory Dysfunction in Healthcare Workers with COVID-19: Prevalence and Associated Factors
Background: The COVID-19 pandemic is a real global health crisis. Its clinical presentation has evolved over time with an increasing number of symptoms. Olfactory dysfunction (OD) has recently been recognized as a frequent symptom relevant to screening for COVID-19, especially in pauci-asymptomatic forms. However, the underlying mechanisms of OD are not yet fully understood. Aim: To determine the prevalence Read More
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