Current Organic Chemistry - Volume 23, Issue 7, 2019

As an alternative to increasingly depleted traditional petroleum fuel, bio-oil has many advantages: high energy density, flexibility, easy storage and transportation. Nevertheless, bio-oil also presents some unwanted characteristics such as high viscosity, acidity, oxygen content and chemical instability. The process of bio-oil upgrading is necessary before utilization as transportation fuels. In addition, the bio-oil has low effective Read More

Recent advances in high-throughput, automated techniques combined with the identification of new therapeutic targets in genome sequencing and molecular biology have generated a need for a large collection of diverse heterocyclic scaffolds. This inspires toward the development of novel reaction sequences and linking strategies to generate libraries of diverse simple to complex heterocyclic systems. In this regard, combin Read More

Interlayer dielectrics with low dielectric constant are the key to unlock the high arithmetic speed of integrated circuit, one of the kernels of modern industry. Polybenzoxazine, derived from benzoxazine precursor, is a new generation of phenolic resin that is considered as an ideal potential candidate for electronic materials due to its unique properties. However, for developing higher speed supercomputers, the dielectric pro Read More

We herein describe the first review which aims to focus soberly the various synthetic methods and chemical reactions of chloroquinoline-3-carbonitrile derivatives. The reactions are subdivided into groups that cover reactions of chloro substituent at 2 or 4 and 2,4 positions, as well as cyano substituent at 3 position and reactions which involve both groups. Most types of reactions have been successfully applied and use Read More

An important approach to the development of new antitumor agents is the synthesis of conjugates containing two or more structural units. Taking this into consideration, vindoline derivatives were coupled with triphenylphosphine, to afford the expected phosphonium salts. The new hybrid entities were characterized by NMR spectroscopy, and their anticancer activity was also evaluated.