Current Organic Chemistry - Volume 16, Issue 24, 2012

The review describes preparation of P,N-bidentate ligands without a P–N bond and their use in asymmetric catalysis. Diverse types of aminophosphines are considered with emphasis on P,N-ferrocene ligands, phosphino-oxazolines and phosphinopyridines. The following major synthetic approaches to aminophosphines and related compounds are summarized: (i) via lithiation, (ii) the use of Grignard reagents, (iii Read More

This review provides an overview of methods that lead to the substitution of halogens from rings of halogenated heterocycles by hydrogen. The first part of the review treats the subject matter from the viewpoint of the method used for the hydrodehalogenation reaction, while the second part is devoted to site selective reductive processes.

Biotransformation is a broad and constantly growing field of biotechnology, which encompasses enzymatic, microbial and biomimetic catalysis. Use of biocatalysis for some chemical synthesis steps has unique advantages over traditional chemistry, most notably the possibility of achieving higher product selectivity under mild process conditions. This review discusses critical aspects of biotransformation of toxic organic compounds Read More

We screened for selective inhibitors of mammalian DNA polymerase (Pol) species from natural products. We then identified compounds that are potential anticancer agents based on Pol inhibition. In this review, the focus is on symbiotic microorganisms that grow on wild marine plants and which could be used as a new screening source for anticancer compounds. The fungal strains were isolated from wild marine plants suc Read More

Solid-emissive materials have found many applications in various fields, especially in the development of organic lightemitting diodes (OLED) and solid-state sensory devices. Currently, the biggest limitation is the availability of highly solid-emissive materials, which meet the requisites of good chemical- and photo-stability. Among all the chromophores developed until now, BODIPY derivatives (4,4-Difluoro-4-bora-3a,4a-diaza-s-i Read More

Chiral (R)-(-) and (S)-(+)-8-amino-5,6,7,8-tetrahydroquinoline, hereafter defined (R)-CAMPY and (S)-CAMPY, have proved to be valuable chiral ligands in Ru(II) precatalysts for the reduction of prochiral ketones by asymmetric hydrogen transfer AHT. These ligands bear chiral information on an alkyl ring fused to a pyridine and therefore have a flat nature, characterized by a high conformational rigidity. It represent the first ap Read More

The formation of oxygenated (quinone) and oxidative (polymer) products in the reaction of selected phenols with hydrogen peroxide catalysed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides ((TAP)FeIIICl) in 3:1 mixture of dichloromethane and hydroxyl ionic liquids (1-(2-hydroxyethyl)-3-methyl imidazolium and 2-hydroxyethyl ammonium ionic liquids) depend on the electron donating and withdrawing group on porphyrin r Read More

The application of photocatalytic reactions in organic synthesis has attracted extensive attentions because of recent developments in environmentally benign synthetic processes. For the first time, an organic pigment (C. I. Pigment Green 8) was used as selective photocatalyst to accomplish the photocatalytic hydroxylation of phenol to catechol (CAT) and hydroquinone (HQ) with the assistance of UV irradiation at r Read More