Current Organic Chemistry - Volume 16, Issue 1, 2012

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Current Organic Chemistry has completed 15 years of its existence and it has become an important journal, indispensable in every institution where research and teaching are being carried on in organic chemistry. It has achieved a very respectable Impact Factor and is often the first choice for authors wishing to publish reviews in a cutting edge field of organic chemistry. I would like to thank the Regional Editor, Executive Editors Read More

Nature's capability of conducting chemical transformations has motivated scientists globally to mimic such processes. One of the fundamental core areas behind this is metal centered catalysis, since many of the known enzymes are in fact metalloenzymes. In this context, the significant enzymatic role of molybdenum in biochemical reactions, such as nitrogen fixation, induced the use of molybdenum complexes as biomi Read More

This is a review of the published papers that focus on the reactivity of carbonyl complexes of molybdenum in low oxidation states (usually zero or two) and possible applications of molybdenum complexes as precursors of catalysts in different reactions of unsaturated organic substrates such as alkenes and alkynes. The following reactions are analyzed: metathesis, metathesis polymerization, free radical reactions of alkenes, hyd Read More

Applications of η5-cyclopentadienyl molybdenum complexes as catalysts for achiral and chiral epoxidation of olefins are reviewed. The discussion is categorized according to the different complex types which arise from the variety of ancillary ligands coordinated to the (η5-C5R5)Mo moiety. The yields and turnover frequencies (TOFs) achieved under standard conditions with these different catalysts have been considered and thus Read More

The purpose of this review is to demonstrate that high valent oxo-molybdenum complexes are excellent catalysts for C-X bond forming reactions, including carbon-carbon, carbon-heteroatom (C-N, C-O, C-S, C-P, C-Br, and C-I), and carbon-hydrogen bonds.

Mo(VI) complexes MoO2X2L2 (X=halide or Me, L neutral ligand) behave as catalysts for olefin epoxidation in the presence of t-butylhydroperoxide (TBHP). The active species results from OH activation of TBHP, which protonates one oxo group and leads to a seven coordinate complex, with a new OOR ligand. It was found that several Mo(II) complexes Cp'Mo(CO)3X (Cp'=C5R5, Cp* or C5H5, Cp) acted as precursors for the sam Read More

Procedures for covalent bonding of ligands to polymer support and their reactions with molybdenum precursors to obtain polymer-supported molybdenum complexes are outlined. These supported molybdenum complexes are used as catalysts for organic transformations such as oxidation of alkenes, phenols, allyl alcohol, ethylbenzene and benzoin, and for polymerization reaction. Higher activity, recyclability and high turn Read More

In most of the chemical and pharmaceutical industrial processes at least one catalytic step is essential during their synthesis. Catalysts speed up chemical reactions but can be recovered unchanged at the end of the reaction. In this respect, heterogeneous catalysts surpass their homogeneous congeners by offering better recyclability as well as an easier separation from the reaction medium. Increasing research Read More

The pseudotrisaccharide allosamidin 1 is a potent family-18 chitinase inhibitor, and it demonstrates biological activities against insects, fungi, and the Plasmodium falciparum life cycle. Compound 1 contains two N-acetylhexosamine residues with the unusual D-allo-configuration and a novel aminocyclitol (i.e. allosamizoline 2), joined by two β-(1→4) glycosidic bonds. Many traditional syntheses of compounds 1-2 and their anal Read More

A series of highly-functionalized 2'-hydroxychalcones have been synthesized using a microwave-assisted Claisen-Schmidt condensation. Conversion of these 2'-hydroxychalcones to their corresponding flavanones was then performed utilizing protic ionic liquids (pIL) and microwave irradiation. This methodology drastically reduces reaction time to 15 minutes compared to typical thermal methods (24 hrs) and is tolerant to a bro Read More