Current Organic Chemistry - Volume 16, Issue 15, 2012

3,3'-disubstituted axially dissymmetric BINOLS, owing to their lower acidity have limited organocatalytic applications in stereoselective transformations. Nevertheless, they serve as potent and immediate precursors to much stronger Bronsted acids e.g. binaphthyl phosphoric acids. The review lists some suitably substituted and sterically demanding BINOLS, their use in organic transformations and possibility to conve Read More

Nitrogen-containing heterocycles, and more specifically the chiral ones, possess various biological and pharmaceutical properties. Among the approaches to these compounds, the organocatalyzed asymmetric multicomponent reaction has emerged as a powerful tool. This review will focus on the later development to chiral dihydropyridines, dihydropyrimidines and quinolizidines via asymmetric organocatalyzed synthesis....

In this review, we have focused our attention on the application of dendrimers as asymmetric catalyst in organic synthesis, which appeared in the literature. Dendrimers have been identified as a promising candidate for catalysis application. The combination of high surface area and high solubility makes dendrimers as useful nanoscale catalysts. The main advantage of the dendritic catalysts is they can be separated from Read More

This review is devoted to the design of new salen type ligands and its applications in the asymmetric catalysis. The main achievements in this field include development of recyclable catalysts, investigation of the mechanism of the secondary alcohols oxidative resolution and the asymmetric Henry reaction, and a study of the synthetic advantages of the salen complex catalysis. The aim of this review is to present an overview Read More

The catalysis by dirhodium paddlewheel complexes has been an area of immense interest and extensive study over the past three decades - not only because most of the catalysts are highly stable to heat, moisture and ambient atmosphere but also for the asymmetric induction in the ylide generation. In this review, we attempt to provide an overview on the general preparation method for most homogeneous chiral dirhodiu Read More