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Volume 2, Issue 1
  • ISSN: 2210-299X
  • E-ISSN: 2210-3007
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Abstract

Nanoencapsulation has gained popularity in recent decades due to its numerous benefits, such as improved stability, oxidation resistance, retention of volatile ingredients, controlled release, delivery of multiple active ingredients in a row, improvement in organoleptic properties, reduction of toxic side effects, and water solubility.

The present study was aimed to prepare eugenol nanoemulsions (EuNEs) using non-ionic surfactant (Tween 80) by ultrasound-assisted techniques and to evaluate the effects of surfactant concentration on their droplets size, polydispersity index (PDI), zeta potential, storage stability, antioxidant, and antibacterial activities. Antimicrobial activity of the prepared nanoemulsions was tested against Gram-positive; and Gram-negative; , and bacteria using well diffusion method.

The results showed that the droplet size decreased after a threshold Tween 80 concentration (10%), while PDI value increased with the increase in surfactant concentration (Tween 80).

The prepared EuNEs exhibited good antibacterial activity against all the four bacterial strains: , and .

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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/content/journals/cis/10.2174/012210299X262244231010050553
2024-01-01
2024-11-26

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/content/journals/cis/10.2174/012210299X262244231010050553
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Effect of Surfactant Concentration on Physicochemical and Antibacterial Properties of Eugenol Nanoemulsions
Curr. Indian Sci. 2, E2210299X262244 (2024); https://doi.org/10.2174/012210299X262244231010050553
/content/journals/cis/10.2174/012210299X262244231010050553
/content/journals/cis/10.2174/012210299X262244231010050553
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  • Article Type:     Research Article
Keyword(s): Antimicrobial activity; Antioxidant activity; EuNEs; Nanoencapsulation; Stability of nanoemulsion; Tween 80

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