Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Functional Foods
  4. Volume 1, Issue 1
  5. Article
Volume 1, Issue 1
  • ISSN: 2666-8629
  • E-ISSN: 2666-8637

Abstract

Background

Olive ( L.) and carob ( L.), which contain considerable amounts of phenolic compounds, are the most important nutritional and therapeutic plants in the Mediterranean basin.

Objectives

The goal of this work is to revalue carob and olive leaves as key sources of polyphenols, hence increasing the value of waste goods.

Methods

In this study, aqueous acetone or ethanol (80% v/v) extracts of olive ( L. cultivar ) and carob ( L.) leaves from Algeria were evaluated for phenolic content, and the extracts were characterized by reverse-phase high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS).

Discussion and Results

The total phenolic content of olive and carob leaf extracts ranged from 5.6 to 23 mg GAE/g. The use of HPLC-ESI-MS to investigate phenolics revealed that the extracts included a variety of phenolic compounds, including 23 compounds in olive leaf extracts and 17 compounds in carob leaf extracts. In olive and carob, the major phenolic components are oleuropein and myricetin rhamnoside, respectively.

Conclusion

According to our findings, and appear to be rich suppliers of natural chemicals. These plants have a lot of potential in terms of medications and functional foods.

© 2023 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/cff/10.2174/2666862901666221208093036
2023-04-01
2024-11-26

  • From This Site

    /content/journals/cff/10.2174/2666862901666221208093036
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. ShahidiF. AmbigaipalanP. Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects-A review.J. Funct. Foods20151882089710.1016/j.jff.2015.06.018
     [Google Scholar]
  2. Lee-HuangS. ZhangL. Lin HuangP. ChangY.T. HuangP.L. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment.Biochem. Biophys. Res. Commun.200330741029103710.1016/S0006‑291X(03)01292‑012878215
     [Google Scholar]
  3. KorukluogluM. SahanY. YigitA. KarakasR. Antifungal activity of olive leaf (Olea Europaea L.) extracts from the Trilye Region of Turkey.Ann. Microbiol.200656435936210.1007/BF03175032
     [Google Scholar]
  4. RanalliA. ContentoS. LuceraL. Di FeboM. MarchegianiD. Di FonzoV. Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.).J. Agric. Food Chem.200654243444010.1021/jf051647b16417301
     [Google Scholar]
  5. PereiraA. FerreiraI. MarcelinoF. ValentãoP. AndradeP. SeabraR. EstevinhoL. BentoA. PereiraJ. Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrançosa) leaves.Molecules20071251153116210.3390/1205115317873849
     [Google Scholar]
  6. SudjanaA.N. D’OrazioC. RyanV. RasoolN. NgJ. IslamN. RileyT.V. HammerK.A. Antimicrobial activity of commercial Olea europaea (olive) leaf extract.Int. J. Antimicrob. Agents200933546146310.1016/j.ijantimicag.2008.10.02619135874
     [Google Scholar]
  7. LongH.S. TilneyP.M. Van WykB.E. The ethnobotany and pharmacognosy of Olea europaea subsp. africana (Oleaceae).S. Afr. J. Bot.201076232433110.1016/j.sajb.2009.12.005
     [Google Scholar]
  8. PaudelS. MagratiT. LamichhaneJ.R. Antimicrobial activity of wild olive crude extracts in vitro. Int. J. Pharm. Sci. Res.20112110113
     [Google Scholar]
  9. AissaniN. CoroneoV. FattouchS. CaboniP. Inhibitory effect of carob (Ceratonia siliqua) leaves methanolic extract on Listeria monocytogenes. J. Agric. Food Chem.201260409954995810.1021/jf302962322978382
     [Google Scholar]
  10. KhalatbaryA.R. ZarrinjoeiG.R. Anti-inflammatory effect of oleuropein in experimental rat spinal cord trauma.Iran. Red Crescent Med. J.201214422923422754686
     [Google Scholar]
  11. HadrichF. MahmoudiA. BouallaguiZ. FekiI. IsodaH. FeveB. SayadiS. Evaluation of hypocholesterolemic effect of oleuropein in cholesterol-fed rats.Chem. Biol. Interact.2016252546010.1016/j.cbi.2016.03.02627019295
     [Google Scholar]
  12. GhomariO. SounniF. MassaoudiY. GhanamJ. Drissi KaitouniL.B. MerzoukiM. BenlemlihM. Phenolic profile (HPLC-UV) of olive leaves according to extraction procedure and assessment of antibacterial activity.Biotechnol. Rep. (Amst.)201923e0034710.1016/j.btre.2019.e0034731193889
     [Google Scholar]
  13. CustódioL. EscapaA.L. FernandesE. FajardoA. AliguéR. AlberícioF. NengN. NogueiraJ.M.F. RomanoA. L. EscapaA.L. FernandesE. FajardoA. AliguéR. AlberícioF. NengN. NogueiraJ.M.F. RomanoA. Phytochemical profile, antioxidant and cytotoxic activities of the carob tree (Ceratonia siliqua L.) germ flour extracts.Plant Foods Hum. Nutr.2011661788410.1007/s11130‑011‑0214‑8
     [Google Scholar]
  14. UysalS. ZenginG. AktumsekA. KaratasS. Chemical and biological approaches on nine fruit tree leaves collected from the Mediterranean region of Turkey.J. Funct. Foods20162251853210.1016/j.jff.2016.02.006
     [Google Scholar]
  15. StavrouI.J. ChristouA. Kapnissi-ChristodoulouC.P. Polyphenols in carobs: A review on their composition, antioxidant capacity and cytotoxic effects, and health impact.Food Chem.201826935537410.1016/j.foodchem.2018.06.15230100447
     [Google Scholar]
  16. MakrisD.P. KefalasP. Carob pods (Ceratonia siliqua L.) as a source of polyphenolic antioxidants.Food Technol. Biotechnol.200442105108
     [Google Scholar]
  17. CustódioL. PatarraJ. AlberícioF. NengN.R. NogueiraJ.M.F. RomanoA. In vitro antioxidant and inhibitory activity of water decoctions of carob tree ( Ceratonia siliqua L.) on cholinesterases, α-amylase and α-glucosidase.Nat. Prod. Res.201529222155215910.1080/14786419.2014.99614725582851
     [Google Scholar]
  18. CorsiL. AvalloneR. CosenzaF. FarinaF. BaraldiC. BaraldiM. Antiproliferative effects of Ceratonia siliqua L. on mouse hepatocellular carcinoma cell line.Fitoterapia2002737-867468410.1016/S0367‑326X(02)00227‑712490228
     [Google Scholar]
  19. HsounaA.B. SaoudiM. TriguiM. JamoussiK. BoudawaraT. JaouaS. FekiA.E. Characterization of bioactive compounds and ameliorative effects of Ceratonia siliqua leaf extract against CCl4 induced hepatic oxidative damage and renal failure in rats.Food Chem. Toxicol.201149123183319110.1016/j.fct.2011.09.03421996303
     [Google Scholar]
  20. KivçakB. MertT. OzturkH.T. Antimicrobial and cytotoxic activity of Ceratonia siliqua L. extracts.Turk. J. Biol.200226197200
     [Google Scholar]
  21. IbrahimA.H. Abd El-BakyR.M. DesoukeyS.Y. Abd-LateffA. KamelM.S. Bacterial growth inhibitory effect of Ceratonia siliqua L. plant extracts alone and in combination with some antimicrobial agents, Sect. Title Microbial.Algal. Fungal Biochem.20131313
     [Google Scholar]
  22. Ben OthmenK. ElfallehW. García BeltránJ.M. EstebanM.Á. HaddadM. An in vitro study of the effect of carob (Ceratonia siliqua L.) leaf extracts on gilthead seabream (Sparus aurata L.) leucocyte activities. Antioxidant, cytotoxic and bactericidal properties.Fish Shellfish Immunol.202099354310.1016/j.fsi.2020.02.00532032761
     [Google Scholar]
  23. MezianiS. OomahB.D. ZaidiF. Simon-LevertA. BertrandC. Zaidi-YahiaouiR. Antibacterial activity of carob (Ceratonia siliqua L.) extracts against phytopathogenic bacteria Pectobacterium atrosepticum. Microb. Pathog.2015789510210.1016/j.micpath.2014.12.00125489722
     [Google Scholar]
  24. SingletonV.L. OrthoferR. Lamuela-RaventósR.M. LesterP. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent.Methods Enzymol.199929915217810.1016/S0076‑6879(99)99017‑1
     [Google Scholar]
  25. MylonakiS. KiassosE. MakrisD.P. KefalasP. Optimisation of the extraction of olive (Olea europaea) leaf phenolics using water/ethanol-based solvent systems and response surface methodology.Anal. Bioanal. Chem.2008392597798510.1007/s00216‑008‑2353‑918762919
     [Google Scholar]
  26. HayesJ.E. AllenP. BruntonN. O’GradyM.N. KerryJ.P. Phenolic composition and in vitro antioxidant capacity of four commercial phytochemical products: Olive leaf extract (Olea europaea L.), lutein, sesamol and ellagic acid.Food Chem.2011126394895510.1016/j.foodchem.2010.11.092
     [Google Scholar]
  27. RyanD. RobardsK. LaveeS. Determination of phenolic compounds in olives by reversed-phase chromatography and mass spectrometry.J. Chromatogr. A19998321-2879610.1016/S0021‑9673(98)00838‑3
     [Google Scholar]
  28. SavareseM. DemarcoE. SacchiR. Characterization of phenolic extracts from olives (Olea europaea cv. Pisciottana) by electrospray ionization mass spectrometry.Food Chem.2007105276177010.1016/j.foodchem.2007.01.037
     [Google Scholar]
  29. KontogianniV.G. CharisiadisP. MargianniE. LamariF.N. GerothanassisI.P. TzakosA.G. Olive leaf extracts are a natural source of advanced glycation end product inhibitors.J. Med. Food201316981782210.1089/jmf.2013.001624044491
     [Google Scholar]
  30. Ortega-GarcíaF. BlancoS. PeinadoM.A. PeragónJ. Polyphenol oxidase and its relationship with oleuropein concentration in fruits and leaves of olive (Olea europaea) cv. ‘Picual’ trees during fruit ripening.Tree Physiol.2008281455410.1093/treephys/28.1.4517938113
     [Google Scholar]
  31. Quirantes-PinéR. Lozano-SánchezJ. HerreroM. IbáñezE. Segura-CarreteroA. Fernández-GutiérrezA. HPLC-ESI-QTOF-MS as a powerful analytical tool for characterizing phenolic compounds in olive-leaf extracts.Phytochem. Anal.20132421322310.1002/pca.2401
     [Google Scholar]
  32. OwenR.W. HaubnerR. HullW.E. ErbenG. SpiegelhalderB. BartschH. HaberB. Isolation and structure elucidation of the major individual polyphenols in carob fibre.Food Chem. Toxicol.200341121727173810.1016/S0278‑6915(03)00200‑X14563398
     [Google Scholar]
  33. EldahshanO.A. Isolation and structure elucidation of phenolic compounds of carob leaves grown in Egypt.Curr. Res. J. Biol. Sci.201135255
     [Google Scholar]
  34. GoharA. GedaraS.R. BarakaH.N. New acylatedflavonol glycoside from Ceratonia siliqua L. seeds.J. Med. Plants Res.20093424428
     [Google Scholar]
  35. FarrD.R. MagnolatoD. LöligerJ. Protection of foodstuffs from oxidation.US Patent 47419151988
  36. LeeJ. JangD.S. KimN.H. LeeY.M. KimJ. KimJ.S. Galloyl glucoses from the seeds of Cornus officinalis with inhibitory activity against protein glycation, aldose reductase, and cataractogenesis ex vivo.Biol. Pharm. Bull.201134344344610.1248/bpb.34.44321372401
     [Google Scholar]
/content/journals/cff/10.2174/2666862901666221208093036
Loading
Characterization of Phenolic Compounds of Olea europaea L. and Ceratonia siliqua L. Leaf Extracts by HPLC-ESI-MS
Curr Func Foods 1, e081222211749 (2023); https://doi.org/10.2174/2666862901666221208093036
/content/journals/cff/10.2174/2666862901666221208093036
/content/journals/cff/10.2174/2666862901666221208093036
Loading

Data & Media loading...


  • Article Type:     Research Article
Keyword(s): Ceratonia siliqua; compounds; HPLC-ESI-MS; medicinal plants; Olea europaea; phenolic; Polyphenols

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test