Current Chinese Chemistry - Volume 2, Issue 3, 2022

Background: Herbal plant-based products and their derived phytochemicals have been used in the complementary and alternative systems of medicine for the treatment of human disorders. Vegetables, fruits, seeds, nuts, coffee, tea, and wine contain significant amounts of coumarin class phytochemicals. Coumarin is found to be present in cassia leaf oil, cinnamon bark oil, lavender oil, and microorganism-derived drugs.Me Read More

Background: ATAD2 is closely related to the occurrence and proliferation of many tumors. Thus, exploring ATAD2 inhibitors is greatly significant for the prevention and treatment of tumors. In this study, the quantitative structure–activity relationship (QSAR) analyses of 57 naphthyridone derivatives were conducted using hologram quantitative structure–activity relationship (HQSAR) and topomer comparative molecular fie Read More

Background: Bacteria cause various infections and are a threat to the health system. This threat is increased due to the resistance of bacteria towards antibacterial drugs. Plants are an important source of drugs including antibacterial agents. Pyracantha crenulata is one important plant known for its different medicinal uses. It contains different phytoconstituents responsible for its medicinal properties.In cholera, ToxT (PD Read More

Background: Benzimidazoles are important heterocyclic compounds having significant attention in the pharmacological industry due to their various biological and dying properties.Objective: 3-(1H-benzo[d]imidazol-2-yl)-2-chloroquinoline, a heterocyclic dye (1), was prepared using o-phenylenediamine and 2-chloroquinoline-3-carbaldehyde in the presence of ceric ammonium nitrate catalyst and hydrogen peroxide un Read More