Current Bioactive Compounds - Volume 18, Issue 8, 2022

Background: Plants from the genus Nymphaea L. have been used for decades to treat various diseases, including dysentery, diarrhea, uterine cancer, gonorrhea, inflammation conditions, etc. The present study aims to critically analyze comprehensive literature on ethnopharmacological uses, phytochemistry, pharmacology, and toxicity of Nymphaea L. Methods: The available information on Nymphaea L. was obtained fro Read More

Background: Vepris dainelli (Rutaceae) is an endemic medicinal plant of Ethiopia, traditionally used for the treatment of abdominal cramps, intestinal worms, skin diseases, and tooth pain. Methods: Roots and fruit extracts were subjected to silica gel column chromatographic separation to afford five alkaloids, reported for the first time from the species. The cytotoxic effects of alkaloids (2-4) were evaluated in vitro agains Read More

Background: Genistein is one of many new cytotoxic drug leads that have been discovered recently. It is a well-studied chemopreventive drug that has attracted the attention of the scientific community due to its favourable effects on grave illnesses in humans such as cancer. Objective: The present study focuses on the methanolic extraction, isolation, and characterization of an isoflavone, genistein, from the weed plant of C Read More

Background: Jordan is a country well-known for its diversity in wild plants, and for many decades, folk medicines have represented part of its cultural heritage. In the present study, investigations have been focused on the therapeutic potential of Silybum marianum and Pergularia tomentosa on type 2 diabetes mellitus. In type 2 diabetes, which is considered a global health problem, the body cannot respond to or p Read More

Background: The search for natural anticancer agents is a worthy scientific research goal, driven by the hope to lessen cancer's tremendous global burden. Objective: This study aimed at evaluating the cytotoxic activity of Gardenia latifolia Ait. (Rubiaceae) against lung (A549) and colon (HCT116) cancer cell lines. Cytotoxicity-guided isolation of the bioactive phytochemicals was conducted, followed by various mechanistic validation Read More

Background: Marine algae produce bioactive compounds, including polyphenols. They have antioxidant, antibacterial, immune regulation and other biological activities. The aim of this study was to examine the antibacterial and antioxidant activities of extracts of five marine algae species: Cystoseira humilis, Halopteris scoparia, Pavonica padina, Sargassum vulgare and Rhodomela confervoides of Bejaia’s coast (northern Al Read More

Background: Boswellia serrata is an important species from the Boswellia genus, which contains a variety of significant phytoconstituents. Numerous applications of the B. Serrata have been mentioned in the literature of the Indian ayurvedic system. Researchers reported abundant pharmacological activities of B. Serrata resins extract. The extract produces synergistic pharmacological activity due to the presence of Read More