Current Bioactive Compounds - Volume 18, Issue 3, 2022

Background: Phytochemicals are pure chemical compounds found to be present in different plants part such as leaves, fruit, flower, seeds and the whole plant. These pure plant-based chemicals are having power to treat all disorders of the human beings and other higher animal species on earth. Flavonoidal compounds are responsible for the attractive color and important biological properties of plant material. Flavonoids a Read More

Background: Many species have already been examined regarding their biological activities, but there are nevertheless many more which merit examination, among them Carduncellus pinnatus (Desf), which is one of the less abundant and the less frequent aromatic plants of Asteraceae species, it is one of the species widely distributed in the Mediterranean region. In the present investigation, chemical composition of ess Read More

Background: Sargassum cristaefolium, as one of the brown seaweeds locally found in Indonesia, is extracted using the serial technique employing different solvents. Methods: S. cristaefolium powder (50 mesh) was extracted with three different solvents, including hexane, ethyl acetate, and methanol. S. cristaefolium powder residue was dried prior to serial re-extraction using different solvents. Three serial extracts were obta Read More

Background: The prevailing multiple drug resistance among the bacterial species is alarmingly rising day to day, becoming a global threat. Many infectious diseases have become untreated due to the development of resistance in bacterial species, which have a considerable impact on mortality. Methods: In this present study, we aimed to synthesize a series of 12 compounds [S1-S12], which are azetidinone derivatives o Read More

Background: Aromatic and medicinal plants have been used to substitute synthetic drugs with natural bioactive products. Objective: The current investigation was conducted to evaluate phenol and flavonoid contents, antibacterial, antioxidant, and anti-hypertensive potentials of three extracts of Margotia gummifera aerial parts. Methods: The antibacterial effect was assessed using the wells agar diffusion method against 11 str Read More

Background: Globularia alypum L. is a Mediterranean plant of the Globulariaceae family which has been used in folk medicine to cure several diseases. Different studies have been done in vitro and in vivo using diverse G. alypum extracts to understand this traditional use. Methods: In this study, Tunisian G. alypum leaf methanol extract (GAME) was chemically identified using LC-ESI-MS, then examined in vitro for its antioxid Read More

Background: Lignans are biologically important phenolic compounds that exist in different levels of various plants; yet, flaxseed is one of the richest sources of such compounds. Lipoxygenase enzymes are associated with many inflammatory-related diseases such as arthritis, allergic asthma, psoriasis, cardiovascular disease, kidney disease, skin diseases, and neuropsychiatric disorders, as in Alzheimer's disease. Not only are t Read More

Objectives: Ruta tuberculata forssk. (Rutaceae) is an aromatic plant widely used in traditional Algerian medicine due to its pharmaceutical virtues against various disorders. This study aims to determine the phenolic profile of aqueous (RAE) and methanol (RME) extracts of R. tuberculata aerial parts and to investigate their acute oral toxicity, as well as their possible antiproliferative and hepatoprotective effects. Methods: Polyph Read More