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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Residues Around the Catalytic Pocket of DdsA Are Important for Isoprenoids Chain Elongation
- Source: Protein and Peptide Letters, Volume 14, Issue 1, Jan 2007, p. 27 - 32
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- 01 Jan 2007
Abstract
Nineteen mutants of decaprenyl diphosphate synthase from Gluconobacter suboxydans were generated and their production of ubiquinones (UQs) was compared to that of the wild type protein. The accessible surface area and the polarity of amino acid around the catalytic pocket wield remarkable influences on the isoprenoid chain elongation of UQs.
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