Identification and Characterization of Trichoplusia ni Furin Truncated Mutant

Lie Wang; Dan Xu; Ming Qian; Guanzhen Yang; Xiangfu Wu

doi:10.2174/092986606775101553

ISSN: 0929-8665
E-ISSN: 1875-5305

Identification and Characterization of Trichoplusia ni Furin Truncated Mutant
Authors: Lie Wang¹, Dan Xu², Ming Qian³, Guanzhen Yang⁴ and Xiangfu Wu⁵
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¹ Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, P.R.China. ² Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, P.R.China. ³ Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, P.R.China. ⁴ Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, P.R.China. ⁵ Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, P.R.China.
Source: Protein and Peptide Letters, Volume 13, Issue 2, Feb 2006, p. 171 - 175
DOI: https://doi.org/10.2174/092986606775101553
- Available online: 01 Feb 2006

Abstract

We report A new prohormone convertase gene of insect origin, Trichoplusia ni furin, which was cloned from BTI-Tn-5B-4 (Tn5) insect cells. We constructed A truncated mutant that lacked Cys-rich repeated segments. Using baculovirus expression system and standard enzymatic assay, we obtained recombinant Tn furin and evaluated aspects of its function.

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2006-02-01

2025-05-21

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Article Type: Research Article

Keyword(s): baculovirus; Cys-rich repeated segment; Tn -5B1-4 insect cells; Trichoplusia ni furin

Identification and Characterization of Trichoplusia ni Furin Truncated Mutant

Abstract

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