Hylins: Bombinins H Structurally Related Peptides from the Skin Secretion of the Brazilian Tree-Frog Hyla biobeba

Mariana S. Castro; Rubens H. Matsushita; Antonio Sebben; Marcelo V. Sousa; Wagner Fontes

doi:10.2174/0929866053405977

ISSN: 0929-8665
E-ISSN: 1875-5305

Hylins: Bombinins H Structurally Related Peptides from the Skin Secretion of the Brazilian Tree-Frog Hyla biobeba
Authors: Mariana S. Castro¹, Rubens H. Matsushita², Antonio Sebben³, Marcelo V. Sousa⁴ and Wagner Fontes⁵
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¹ Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil. ² Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil. ³ Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil. ⁴ Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil. ⁵ Brazilian Center for Protein Research, Department of Cell Biology, University of Brasília, Brazil.
Source: Protein and Peptide Letters, Volume 12, Issue 1, Jan 2005, p. 89 - 93
DOI: https://doi.org/10.2174/0929866053405977
- Available online: 01 Jan 2005

Abstract

Two hemolytic peptides were isolated from the skin secretion of the Brazilian Hylidae frog Hyla biobeba, using reversed-phase chromatographic procedures. Hylins b1 and b2 exhibit short linear polypeptide chains, a large number of hydrophobic residues, amidated C-termini and hemolytic properties. These two novel peptides are the first examples of bombinins H-like peptides isolated from anurans species not related to Bombina species.

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2005-01-01

2025-05-22

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Article Type: Review Article

Keyword(s): amphibian; hemolytic peptides; hyla; hylins; skin secretion

Hylins: Bombinins H Structurally Related Peptides from the Skin Secretion of the Brazilian Tree-Frog Hyla biobeba

Abstract

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