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- Volume 14, Issue 8, 2024
Natural Products Journal, The - Volume 14, Issue 8, 2024
Volume 14, Issue 8, 2024
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Screening and Identification Quality Markers for Antioxidant Activity of Tetrastigma hemsleyanum from Different Origins using Spectrum-effect Correlation Analysis
Authors: Jiahao Fang, Shuyao Li, Feng Yin, Lingxia Peng, Hongju Li, Lijun Yang, Qiang Miu, Zongsuo Liang and Xiaodan ZhangBackground: Tetrastigma hemsleyanum (THL) is a traditional medicinal plant with various biological activities, it has been validated that several THL extracts have strong pharmacological activities. Until now, there is no complete and systematic germplasm identification and quality evaluation standard. Objective: Establishing fingerprint spectra of THL from different sources, evaluating their antioxidant activity and identifying q Read More
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Moringa oleifera and its Secondary Metabolites: Chemistry, Properties and Antidiabetic Potentiality
Authors: Dilipkumar Pal, Takeshwar and Sujoy ThakurSecondary metabolites present in different natural resources possess multiple biological activities. Diabetes is one of the leading disease all over the world in current time, and higher in numbersthan the deadliest cancer disease. According to the WHO about 422 million people are suffering from diabetes and most of them are even unaware that they are living with the condition. In recent times research in natural medicinal Read More
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Antibacterial Polyketides from the Plant Endophytic Fungus Fusarium sp.
Authors: Ru Wang, Ying Shi, Qianqian Liu, Liyan Sun and Ling LiuBackground: Endophytic fungi have been recognized as new sources of natural products with a variety of biological activities, providing lead compounds for drug discovery and development. Objective: The objective of this study is to isolate and identify the secondary metabolites from the plant endophytic fungus Fusarium sp. HJY2 and evaluate their antibacterial activities. Methods: The compounds were isolated and purifie Read More
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Pharmacological Approaches and Herbal Interventions for Alzheimer's Disease
This comprehensive review extensively examines the utilization of herbal remedies and pharmacological techniques for managing Alzheimer's disease (AD). It delves deeply into the active constituents and modes of operation of diverse herbal medications such as Withania somnifera, Bacopa monnieri, Ginkgo biloba, and Curcuma longa, emphasizing their qualities in reducing inflammation, acting as antioxidants, and s Read More
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An Updated Review on the Role of Phytoconstituents in Modulating Signalling Pathways to Combat Skin Ageing: Nature’s Own Weapons and Approaches
Authors: Mayur Porwal, Vaibhav Rastogi, Phool Chandra and Swati ShuklaVarious geographical areas exhibit varying degrees of prevalence and severity of dermatological issues. The most commonly observed skin issues among adolescents during their growth period on a global scale encompass dry skin, dyspigmentation, wrinkles, fungal infections, as well as benign and malignant tumors. These conditions arise as a consequence of diminished functional capacity and heightened skin susceptibility. The Read More
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Caenorhabditis elegans as an Outstanding Model to Explore Flavonoids Under Stress Conditions
Plants produce promising chemicals called secondary metabolites in response to stress, which protect against oxidative damage in both plants and humans. Reactive oxygen species (ROS) levels combined with an imbalance in the antioxidant responses can trigger oxidative stress that is related to many conditions such as Alzheimer's disease, diabetes, and cancer. One way to counteract or avoid the stress excess is by flavonoid Read More
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The Effect of Circulating Exosomes Obtained from Young and Old Individuals on the Aging related hTERT and P16 Expression in Hematopoietic Stem Cells
Introduction: Functional reduction of telomeres can induce DNA damage response through cell cycle checkpoints and contribute to the senescence of stem cells. The effect of exosomes on the aging and rejuvenation of hematopoietic stem cells (HSCs) is not well known. Therefore, the present study is designed to examine the impact of plasma exosomes derived from young and old individuals on hTERT and P16 expression invol Read More
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