Natural Products Journal, The - Volume 14, Issue 3, 2024

Background: Cancer is one of the leading causes of death worldwide. Therapy for cancer has remained a challenge for a very long period of time, though developments of various treatment strategies have been introduced. However, Curcuma longa L (Turmeric) attains major attention to cure cancer due to its phytoconstituents which can be used in the treatment of various cancers. Due to the wide availability and minimal adv Read More

Hesperidin is one of the most well-known, naturally occurring flavonoids with antioxidant and anti-inflammatory effect, occurring in high concentrations in citrus fruits. Citrus fruits and juices are widely consumed worldwide and are readily available dietary sources for their intake. Its use has been associated with a great number of health benefits, including antioxidant, antibacterial, antimicrobial, antiinflammatory and Read More

Background: The active secondary metabolites of various Kalanchoe species are promising for controlling insects and other agricultural pests. Objective: This study aimed to evaluate the mortality and immune responses of the leafcutter ant Atta sexdens (L.) after treatment with Kalanchoe ×laetivirens (Desc.) aqueous extract. The effects on an aquatic organism used as a bioindicator, Chironomus xanthus (Rempel), were als Read More

Background: Medicinal plants and herbs constitute rich sources of flavoring, and aromatic compounds, namely phytochemicals, which have many positive impacts on human health, such as antioxidant, anticancer, antimicrobial, anti-inflammatory, cardioprotective, and neuroprotective properties. Such bioactive compounds may be considered lead compounds that can be introduced in the drug design process to obtain Read More

Background and Aims: Diabetes mellitus is a chronic metabolic disorder affecting global public health. Since ancient, natural-based compounds are widely used for multiple indications of diabetes. Methods: The natural-based (-)-Epicatechin has enormous biological functions including antioxidant and anti-inflammatory activities. This review mainly focuses on the importance of epicatechin in the control of pathogenesis involved in Read More

Piperine, an alkaloid from black pepper, has demonstrated diverse pharmacological properties and potential therapeutic applications. Piperine content varies with the pepper plant and ranges from 2 to 7.4% in black pepper. Piperine possesses remarkable biological properties, including antioxidant, anti-inflammatory, antibacterial, anticancer, neuroprotective, and hepatoprotective qualities. Its ability to affect numerous s Read More

Background: Methotrexate (MTX) is a widely used medication for treating various conditions, including skin infections, inflammatory diseases, autoimmune disorders, and malignancies. However, prolonged and extreme use of MTX can lead to detrimental effects on multiple organs. Green Chiretta (GC) is a traditional medicinal plant known for its anti-inflammatory, antioxidant, and immunostimulatory properties. Objective: Read More

Background: Marine fungi have been proven to be a new arsenal for the discovery of valuable secondary metabolites. Method: Fungus strain Aspergillus terreus DM62 was initially fermentated using solid corn medium and PDA liquid medium. Subsequently, extensive chromatographic methods were applied to isolate the fermentation cultures of DM62, and the chemical structures of isolate compounds were elucidated Read More