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- Volume 13, Issue 8, 2023
Natural Products Journal, The - Volume 13, Issue 8, 2023
Volume 13, Issue 8, 2023
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Antibacterial and Antioxidant Superoxide Anion Radical Inhibitors from Myrmecodia pendans: An In silico Study
Authors: Zenika F. Ramadhanty, Dikdik Kurnia, Boima Situmeang, Mieke Hemiawati and Nur AsmahBackground: Ant-nest (Myrmecodia pendans) is an epiphytic plant that can prevent several diseases, including bacterial infections. Diarrhea is caused by Escherichia coli bacteria, while infections in the oral cavity can be caused by Enterococcus faecalis bacteria. Antibacterial activity is also influenced by conditions of Reactive Oxygen Species (ROS). Antioxidants are needed to inhibit the formation of excess ROS in the body. Read More
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Pharmacology, Ethnopharmacology, and Phytochemistry of Medicinally Active Moringa oleifera: A Review
Authors: Nitin Kumar and Shikha SharmaMoringa oleifera (MO), which belongs to the family Moringaceae, is a significant medicinal plant that is also one of the species farmed in the greatest quantity worldwide. All its components, including its leaves, roots, seeds, flowers, bark, stems, and green pods, have a wide range of medicinal properties and are exceptionally high in nutritional content. Some of the important medicinal properties of the plant include a Read More
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Garcinia livingstonei T. Anderson: A Potential Source for Bioactive Constituents
Authors: Fatma H.M. Nossier, Rehab M.S. Ashour, Azza R. Abdel-Monem and Ali M.A. ElsayedGarcinia livingstonei T. Anderson (African mangosteen) is a member of family Clusiaceae and is native to South Africa. It is distributed from Malaysia to the Philippines, Burma and India. The plant is used traditionally in the treatment of diarrhea. It contains various chemical constituents belonging to biflavonoids, benzophenones and xanthones. Garcinia livingstonei is reported to possess beneficial pharmacological activities as anti- Read More
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Assessment Methods for Various Hepatotoxicities and their Experimental Models: A Review
More LessGlobally, liver diseases are a significant public health concern, necessitating the development of new chemicals that can aid in their treatment or prevention. As a result, scientists have been looking for natural and artificial compounds with hepatoprotective effects. The key objective of this manuscript is to provide details on several techniques and models for determining liver toxicity. The data has been collected for the man Read More
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Modulatory Effects of Mangiferin Isolated from Aquilaria Plants on Human Cytochrome P450 Enzyme (CYP) Activities In vitro and In silico Studies
Background: Mangiferin has been identified as one of the major active constituents of Aquilaria plants. It was reported to have several promising chemotherapeutic potentials. Our preliminary data suggested that Aquilaria plant water extracts inhibited several cytochrome P450 (CYP) isoenzymes in vitro. Objective: This study aimed to investigate the modulatory effects of mangiferin on six major drug metabolizing CYP Read More
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Fenugreek (Trigonella foenum-graecum L.) Modulates Energy Metabolism and Anti-inflammatory Response in Obesity via Combinatorial Analysis
Authors: Fong Fong Liew, Theysshana Visuvanathan and Shalini VellasamySince ancient times, fenugreek has been utilized as a dietary condiment as well as for its various therapeutic properties. The goal of this study is to look at the function of fenugreek in regulating obesity metabolism by providing a global picture of gene networks and pathways. The buildup of fat in adipose tissue and other internal organs is a hallmark of obesity, a long-term carbohydrate and lipid metabolic disorder. The fenugree Read More
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Review on Diabetic Complications and their Management by Flavonoids and Triterpenoids
Authors: Shivam, Asheesh K. Gupta and Sushil KumarDiabetes mellitus, together with its numerous consequences, is rapidly becoming a major health issue. Natural products are secondary metabolites found in plants that have a wide range of biological functions. The development of anti-diabetic medications derived from natural compounds, particularly those derived from plants having a documented folk-use history in the treatment of diabetes, is gaining traction. Many studi Read More
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Traditional Uses, Phytochemistry, Pharmacology, and Toxicology of Erigeron floribundus (Kunth) Sch. Bip.: A Review
Erigeron floribundus (Kunth) Sch. Bip. is a reputed medicinal plant widespread all over the world and used traditionally in the treatment of several diseases and infections such as skin disorders, malaria, and gastrointestinal infections. The purpose of this review is to provide a comprehensive overview of traditional uses, phytochemistry, pharmacological activity, and toxicological profile of E. floribundus, and to direct further st Read More
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Trapa natans L.: A Journey from Traditional to Contemporary Therapies - A Review
Authors: Zartaj W. Banu, Debaprotim Dasgupta, Iswar Hazarika, Damiki Laloo and Jun Moni KalitaTrapa natans (Family: Trapacea) is an edible and ornate plant in warm, temperate regions of Asia and Europe. Extracts of different parts, as well as the whole herb itself, have traditionally been used to treat many ailments. Current review aims at documenting, finding research gaps, and critically appraising the contemporary information on T. natans based on botanical account, traditional use, reported bioactive constituents, toxici Read More
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