Mini-Reviews in Organic Chemistry - Volume 12, Issue 4, 2015

This review presents most of the literature data about synthesis and biological activity of pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial, anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic derivatives is the main reason for Read More

BINOL and its derivatives as a class of important and attractive compounds have been widely used in asymmetric synthesis. They could not only play as a part of chiral ligands, but also work well as organocatalysts. This review mainly focused on the recent progress in BINOL mediated asymmetric reactions including C-C bond forming reactions and C-hetero bond forming reactions.

This review reports the chemistry of 2,3-disubstituted N-H aziridines to Five and sixmemberd N-heterocycles. Emphasis will be put on the aspects of stereo- and regioselectivity of appropriate reactions such as 1,3-dipolar, ring expansion reactions as well as C-C or C-N bond cleavage of aziridine ring.

Benzoxazepine is a bi-cyclic heterocyclic compound of a benzene ring fused to an oxazepine ring. Various benzoxazepine derivatives have been synthesized and evaluated for various biological activities. Some analogs derivatives have shown potent biological activities and may be considered as lead molecule for the development of future drugs. This review highlights the different biological activities like anticonvulsant, antimic Read More

Fullerenes being allotropes of carbon, have been considered as new class of molecules. Unlike diamond and graphite, this is made up of hollow carbon cage structure. The idea of spheroidal cage structures of C60 arose from construction of geodesic domes made by renowned architect Buckminster Fuller. Although fullerenes have low solubility in physiological media they finds promising biological applications. The photo, Read More

α-Halo ethers used in the protection of alcohols for the years 2012 - 2014 have been reviewed. The conditions for formation and cleavage of protected alcohols are presented in tables. The α-halo ethers that have been reviewed are: benzyloxymethyl chloride (BOMCl), ethoxymethyl chloride (EOMCl), 2-methoxyethoxymethyl chloride (MEMCl), methoxymethyl bromide (MOMBr), methoxymethyl chloride (MOMCl) and 2- Read More

The title amidines are group of compounds containing both N´-substituted amidine moiety and aromatic amine group. This review collects all available information of syntheses, physicochemical properties and synthetic uses of these amidines.