Mini-Reviews in Organic Chemistry - Volume 12, Issue 2, 2015

Nowadays, scientists need to work with non-contaminating technologies. Some approaches include the use of multicomponent reactions (MCRs), and solid and reusable catalysts. Through MCRs it is possible to work without isolating intermediate products, so the use of auxiliary solvents is minimized. Furthermore, catalysis by heteropolycompounds is a field of increasing importance worldwide. Heteropolycompounds are eff Read More

Alkyl nitrites are inexpensive, mild, relatively stable and easy-to-handle alkyl esters of nitrous acid, that can be prepared simply and used in various synthetic reactions. Alkyl nitrites were discovered in the 19th century and were initially used as medical vasodilators. After several years it was observed, that alkyl nitrites are useful chemical reagents, especially as efficient NO source, consequently these were used for diazotizati Read More

Intramolecular Diels-Alder reactions have become commonly employed transformations in the repertoire of the synthetic organic chemist. Variants of this reaction, which incorporate heteroatoms in the diene and dienophile, are also popular. Surprisingly, one of the least utilized intramolecular Diels-Alder cycloadditions utilizes a carbonyl (either an aldehyde or ketone) as a dienophile. While aldehyde dienophiles are routinely use Read More

Glycerol, a major co-product in the process of biodiesel production, is a promising precursor to a variety of high value fine chemicals such as glyceric acid, dihydroxyacetone, lactic acid and tartronic acid via the corresponding chemoselective oxidation reactions. One of the prospective routes to selectively oxidize glycerol and yield products with good selectivity is the use of nano-sized metal particles as heterogeneous c Read More

Benzimidazoles and its derivatives are an important group of heterocyclic compounds that show a wide range of pharmacological properties such as antitumor, antimicrobial, antihypertensive, antiviral, antiulcer, anticonvulsant, antiinflammatory activities etc. These diverse biological applications of benzimidazole compounds have motivated new efforts in search for novel derivatives with improved biological activity an Read More

This review covers novel cyclopeptides isolated from marine organisms published in literature since 2007, together with the relevant structure, biological activity, source organisms and country of origin. Structure- activity relationship, biosynthetic studies, isolation procedures, and chemical synthesis, have been included.