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- Volume 26, Issue 11, 2020
Current Pharmaceutical Design - Volume 26, Issue 11, 2020
Volume 26, Issue 11, 2020
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Current Nanoparticle Approaches in Nose to Brain Drug Delivery and Anticancer Therapy - A Review
Nanoparticles (NPs) are unique may be organic or inorganic, play a vital role in the development of drug delivery targeting the central nervous system (CNS). Intranasal drug delivery has shown to be an efficient strategy with attractive application for drug delivery to the CNS related diseases, such as Parkinson's disease, Alzheimer 's disease and brain solid tumors. Blood brain barrier (BBB) and blood-cerebrospinal flui Read More
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Recent Nano-based Therapeutic Intervention of Bioactive Sesquiterpenes: Prospects in Cancer Therapeutics
In the recent scenario, nanotechnology-based therapeutics intervention has gained tremendous impetus all across the globe. Nano-based pharmacological intervention of various bioactive compounds has been explored on an increasing scale. Sesquiterpenes are major constituents of essential oils (EOs) present in various plant species which possess intriguing therapeutic potentials. However, owing to their poor physico Read More
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Therapeutic Nanoemulsion: Concept to Delivery
Authors: Md. A. Barkat, Harshita, Md. Rizwanullah, Faheem H. Pottoo, Sarwar Beg, Sohail Akhter and Farhan J. AhmadNanoemulsions (NEs) or nanometric-scaled emulsions are transparent or translucent, optically isotropic and kinetically stable heterogeneous system of two different immiscible liquids namely, water and oil stabilized with an amphiphilic surfactant having droplet size ranges up to 100 nm. They offer a variety of potential interests for certain applications: improved deep-rooted stability; excellent optical clarity; and, enhance Read More
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Lipid-Based Nanosystem As Intelligent Carriers for Versatile Drug Delivery Applications
Authors: Harshita, Md. A. Barkat, Sabya S. Das, Faheem H. Pottoo, Sarwar Beg and Ziyaur RahmanThe contemporary drug discovery research shows that most of the drug candidates are highly potent, but showing poor aqueous solubility leads a variety of challenges for formulation scientists to develop a suitable formulation to improve the systemic bioavailability of such drugs. Lipid-based nanocarriers act as a major and most projecting approach overcoming the limitations which affect several physiochemical properties of Read More
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Surface-Engineered Cancer Nanomedicine: Rational Design and Recent Progress
Authors: Javed Ahmad, Ameeduzzafar, Mohammad Z. Ahmad and Habban AkhterCancer is highly heterogeneous in nature and characterized by abnormal, uncontrolled cells’ growth. It is responsible for the second leading cause of death in the world. Nanotechnology is explored profoundly for sitespecific delivery of cancer chemotherapeutics as well as overcome multidrug-resistance (MDR) challenges in cancer. The progress in the design of various smart biocompatible materials (such as polymers, lipids an Read More
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Exciting Potential of Nanoparticlized Lipidic System for Effective Treatment of Breast Cancer and Clinical Updates: A Translational Prospective
Authors: Ranjit K. Harwansh, Shiv Bahadur, Rohitas Deshmukh and Md. A. RahmanBreast cancer (BC) is a multifactorial disease and becoming a major health issue in women throughout the globe. BC is a malignant type of cancer which results from transcriptional changes in proteins and genes. Besides the availability of modern medicines and detection tools, BC has become a topmost deadly disease and its cure still remains challenging. Nanotechnology based approaches are being employed for the diagnosi Read More
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Polymer-Lipid Hybrid Nanoparticles: A Next-Generation Nanocarrier for Targeted Treatment of Solid Tumors
Authors: Md. Rizwanullah, Meraj Alam, Harshita, Showkat R. Mir, Mohd. M.A. Rizvi and Saima AminAt present, cancer is the most deadly disease and one of the most common causes of death worldwide providing different obstacles to chemotherapy including non-specific biodistribution of chemotherapeutic drugs, dose-related adverse effects, development of metastasis and chemoresistance. Nanoparticle-based targeted delivery of chemotherapeutics gained enormous attention in the treatment of solid tumo Read More
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Nanomedicines in Diagnosis and Treatment of Cancer: An Update
Nanomedicine has revolutionized the field of cancer detection and treatment by enabling the delivery of imaging agents and therapeutics into cancer cells. Cancer diagnostic and therapeutic agents can be either encapsulated or conjugated to nanosystems and accessed to the tumor environment through the passive targeting approach (EPR effect) of the designed nanomedicine. It may also actively target the tumor e Read More
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Volumes & issues
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Volume 31 (2025)
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Volume 30 (2024)
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Volume 29 (2023)
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Volume 28 (2022)
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Volume 27 (2021)
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Volume 26 (2020)
- Issue 46
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- Issue 44
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- Issue 28
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- Issue 22
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- Issue 20
- Issue 19
- Issue 18
- Issue 17
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- Issue 15
- Issue 14
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- Issue 12
- Issue 11
- Issue 10
- Issue 9
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- Issue 7
- Issue 6
- Issue 5
- Issue 4
- Issue 3
- Issue 2
- Issue 1
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Volume 25 (2019)
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Volume 24 (2018)
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Volume 23 (2017)
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Volume 22 (2016)
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Volume 21 (2015)
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Volume 20 (2014)
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Volume 19 (2013)
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Volume 18 (2012)
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Volume 17 (2011)
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Volume 16 (2010)
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Volume 15 (2009)
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Volume 14 (2008)
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Volume 13 (2007)
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Volume 12 (2006)
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Volume 11 (2005)
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Volume 10 (2004)
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Volume 9 (2003)
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Volume 8 (2002)
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Volume 7 (2001)
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Volume 6 (2000)
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