Current Organic Synthesis - Volume 14, Issue 7, 2017

Background: Xanthenes are a class natural and synthetic heterocyclic compounds that exhibit a broad spectrum of biological and synthetic applications. The readership of this review paper will consist of chemists involved with organic chemistry, synthetic organic chemists, pharmacists and biochemists. Objective: This review aims to present an overview of the chemical aspects of low molecular weight xanthenes and the Read More

Background: The Diels-Alder reaction has played a fundamental role in advancing synthetic chemistry over the years and continues to greatly impact modern synthetic methodology. Ever increasing interest in the application of ionic liquids (ILs) as catalyst and solvents in organic synthesis has provided the impetus to explore their application in Diels-Alder chemistry with the goal to improve efficiency as well as chemo-, regi Read More

Background: Chemists have been interested in light as an energy source to induce chemical reactions since the beginning of scientific chemistry. The organic photochemical reactions do not require toxic or polluting reagents so these reactions presented perspectives in the context of green chemistry and sustainable processes. Objective: The largest classical divisions of organic chemistry are constituted by heterocycles. The Read More

Background: In 1996, the Nobel Prize in Chemistry was awarded jointly to Robert F. Curl Jr., Sir Harold W. Kroto, and Richard E. Smalley for their discovery of fullerenes. This ignited the research enthusiasm on the fullerene and lasted for two decades. However, reactions for modifying the surface of fullerene were not summarized completely although a great deal of fullerene derivatives had already been synthesized via th Read More

Background: Metathesis reactions represent an attractive and powerful tool for the synthesis of new carbon-carbon double bonds. The development of ruthenium complexes allows to perform the transformation in both organic and polymer chemistry. Indenylidene catalysts constitute a very important part of this area, as they have been found to be resistant to harsh reaction conditions (temperature and pre Read More

Aim and Objective: Chromenes are one of the most demanded compounds that are recognized for their unique pharmacological and biological activities. This report illustrates the synthesis of new chromene series and chromene based azo chromophores as first example and examines their biological applications in order to explore their possible biological and cytotoxic activities. Material and Method: Using multicomponent m Read More

Background: Hydrazonoyl halides are useful for the synthesis of several heterocyclic derivatives. Thiadiazoles are a significant category of heterocyclic organic compounds with comprehensive range of biological accomplishments. Method: New bisthiadiazoles were prepared by the reaction of hydrazonoyl derivatives with methyl-2- arylidene hydrazinecarbodithioates in dioxane and in the presence of triethylamine. T Read More

Background: pyrazolo[3',4':4,5]pyrimido[1,6-b][1,2,4]-triazines have been found to possess a wide range of medical activities. Objective: we interested to synthesis a new series of pyrazolo[3',4':4,5]pyrimido[1,6-b][1,2,4]triazines via the reaction of 1,3-diphenyl-4-hydrazino-pyrazolo[3,4-d]pyrimidine with ethyl aroyl pyrovates and invistigate thier antimicrobial activity. Not only the biological activity is our aim but also, to el Read More

Aim and Objective: Amides are a very important class of organic compounds. As a type of important amides, arylacetamides have gained considerable attention since their pharmacological and biological activities. Therefore, the development of new methods for the synthesis of aryl acetamides is of significant interest among organic chemists. Material and Method: Using N-methoxymethyl-N-methylcarbamoyl(trimeth Read More