Current Organic Synthesis - Volume 14, Issue 2, 2017

With its introduction as a moulding material in 1940s, the polyamides (PAs) have been transformed into true engineering thermoplastics over a period of time. Owing to high thermal and chemical resistances in combination with exceptional mechanical durability, these classes of polymers have come a long way in establishing themselves as materials of choice for diverse application types. The recent technical advancemen Read More

Poly lactic acids (PLA) received greater attention among other biodegradable plastics as they exhibit higher strength, stiffness, molecular weight and biocompatibility. PLA are polymers in which the stereo chemical structures are modified by polymerizing according to different versatile and flexible applications. The increased demands for PLA resins create a promising and attractive positive impact on the global agricultural e Read More

The amounts of plastics consumed annually all over the world have been growing substantially. Although low density, strength, user-friendly designs, processing capabilities, long life, as well as light weight coupled with high cost-effectiveness make plastics very promising candidates for several applications, they however have ecological issues in terms of waste disposal which has become a major worldwide problem. In f Read More

In previous years natural fibers are frequently used to reinforce materials. The biodegradability is the main advantage of natural fibers. The disadvantage of using natural fibers in polymer composite material is their poor adhesion ability with a polymeric matrix which affects the various physical and mechanical properties of the composite material. To overcome this disadvantage, the surface of the natural fibers needs to Read More

Development of a new polymer from renewable resources is getting serious attention from researchers due to the environmental issue caused by petroleum based polymer. The aim of this paper is to study the behavior of sugar palm starch (SPS) based thermoplastic containing agar in the range from 10 to 40 wt%. The thermoplastics were melt-mixed and then hot pressed at 140 oC for 10 minutes followed by flexural, imp Read More

In the current scenario, the availability of safe and clean drinking water is decreasing day by day. To overcome this difficulty, Nanotechnology has been undertaken to explore various efficient ways for treatment of waste water in a more precise and accurate way with the support of various nanomaterials. Nanoparticles (NPs) have huge potential that enables them to participate in waste water treatment and/or water purifica Read More

Biofibres have gained a considerable attention due to benefits such as environmentally friendly, renewability, biodegradability, low weight and cost. Although many researches have been done on sugar palm fibres (SPF), there are few studies on characterizing their micromechanical properties by using nanoindentation. The hardness and elastic modulus of isolated SPF is 11.3±0.545 MPa and 149±4.96 MPa respectively. The har Read More

In the recent years, the research about polyurethane (PU) composites (thermoplastic, thermoset, biobased polyurethane with synthetic fibers (glass, aramid and carbon) and natural fibers used as reinforcement of polymers has been increased due to their biodegradability, lightness, reduced cost and favorable mechanical properties. Unique mechanical, thermal, and chemical properties of Polyurethanes (thermoset/t Read More

Carbon nanotube (CNT) is a promising allotrope of carbon having exceptional mechanical, electrical, thermal and multifunctional properties. Applications of CNTs are increased when it is chosen as an effective filler in polymer composites. The chemical functionalized CNTs are more compatible as reinforcing agent in polymer composites due to its polar nature. This review involves the preparation, characterization an Read More

Development of new bio- based composites from renewable resources is getting wide attention from researchers due to environmental issue caused by traditional composites. Rice husk is a new potential renewable source of fillers for bio-composites to produce green products. Rice husk is the outer sheath surrounding rice grains during their growth. The aim of this work is to systematically review the parameters that affe Read More

Background:α-Aminophosphonates are an important class of compounds in medicinal chemistry with a wide range of biological effects. Despite the numerous synthetic methods for α-aminophosphonates reported in literature, there is still a need for the development of a simpler and greener protocol, for high throughput library synthesis. Objective: The primary objective of this work was to develop a simple, mild, eco-benign a Read More

Background: (-)-Tatarinoids A, B, and C are 3 of 19 compounds that have been isolated from the rhizome of the plant Acorus tatarinowii. Used in Chinese medicine, Acorus tatarinowii possesses pharmacological effects on the central nervous system by regulating cyclic adenosine monophosphate (cAMP) activity. Previously published computational studies suggested R configurations for all three natural products. N Read More

New 5-oxazolones have been synthesized via N-protected amino acids which were prepared from various aryl acyl halides and L-amino acids, with DCC. Then, we studied the ring opening reactions of 5-oxazolones with nucleophilic attack by primary aryl amines to obtain new racemic benzamide derivatives. All new synthesized compounds have been characterized by FTIR, 1H, 13C NMR, GC/MS, LC/MS and Qtof analyse Read More

Background: Pyrimidines are an important component of nucleic acids and they have been used as building blocks in pharmaceuticals for the synthesis of antiviral, antineoplastic, antibacterial, and antifungal agents. Similarly, the related thiouracil derivatives are potential therapeutics as antiviral, anticancer, and antimicrobial agents. For example, S-alkylation and N-alkylation products have been recently reported as novel Read More

Objective: The objective of this study was to provide experimental chemists with useful guidance for proper choice of a reasonable cyclization precursor in macrolactonization in which there are several options in disconnection analysis. Method: A combination of DFT calculations and MD simulations was used to achieve the aim. In the former method, (1) structures having a local minimum energy near the macrocyclic stru Read More

Background: N-Heterocycles are of special interest because, many natural and synthetic bioactive compounds are found to be N-containing heterocycles and they constitute an important class of pharmacophores in medicinal chemistry. Recently, 1,2,3-triazoles have been found to possess a vast range of vital applications in the agrochemical, pharmaceutical, and materials field. In addition, various compounds of th Read More