Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Medical Imaging
  4. Volume 20, Issue 1
  5. Article
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
file format pdf download PDF
side by side viewer icon HTML

Abstract

Introduction:

Portal vein size and hemodynamics can be altered in patients with portal hypertension. Elastography for liver stiffness has been proposed as a potential predictor of portal hypertension. However, the relationship between liver stiffness measured using point shear wave elastography (pSWE) and portal vein diameter and Doppler parameters remains unclear. Therefore, this observational study aimed to investigate the correlation between liver ultrasound pSWE and portal vein hemodynamics in healthy participants.

Methods:

Twenty-five healthy men with no underlying medical conditions and who were not on regular medications were enrolled in the study. Liver stiffness, portal vein diameter, and Doppler parameters were measured using ultrasound EPIQ Elite with a curved-array transducer (C5-1 MHz) equipped with pSWE and Doppler imaging. Real-time pSWE measurements were taken from the liver. Portal vein diameter and Doppler parameters were measured in a longitudinal view of the extra-hepatic segment. Spearman correlation was used to assess the association between liver pSWE and portal vein diameter as well as Doppler parameters, with a significance level set at < 0.05.

Results:

There was no significant correlation between liver stiffness and portal vein diameter (p = 0.67) or Doppler parameters, including peak systolic velocity (p = 0.89), end-diastolic velocity (p = 0.65), and resistive index (p = 0.86).

Conclusion:

Our findings suggest no direct correlation between liver stiffness measured using pSWE and portal vein hemodynamics in healthy adults. Further studies are warranted to investigate the relationship between liver pSWE and the hemodynamics of portal veins in patients with liver diseases.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/cmir/10.2174/0115734056267877231026102925
2023-11-06
2025-01-28

  • From This Site

    /content/journals/cmir/10.2174/0115734056267877231026102925
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

/deliver/fulltext/cmir/20/1/e15734056267877.html?itemId=/content/journals/cmir/10.2174/0115734056267877231026102925&mimeType=html&fmt=ahah

References

  1. ScaglioneS. KliethermesS. CaoG. ShohamD. DurazoR. LukeA. VolkM.L. The epidemiology of cirrhosis in the United States a population-based study.J. Clin. Gastroenterol.201549869069610.1097/MCG.000000000000020825291348
     [Google Scholar]
  2. RobinsonK.A. MiddletonW.D. AL-SukaitiR. TeefeyS.A. DahiyaN. Doppler sonography of portal hypertension.Ultrasound Q.200925131310.1097/RUQ.0b013e31819c868519276931
     [Google Scholar]
  3. BarrR.G. FerraioliG. PalmeriM.L. GoodmanZ.D. Garcia-TsaoG. RubinJ. GarraB. MyersR.P. WilsonS.R. RubensD. LevineD. Elastography assessment of liver fibrosis.Ultrasound Q.20163229410710.1097/RUQ.000000000000020927233069
     [Google Scholar]
  4. LeeS.M. KimM.J. YoonJ.H. HongW. HaH.I. LeeK. ChoeJ.Y. LeeJ.W. YoonS.Y. HanJ. Comparison of point and 2-dimensional shear wave elastography for the evaluation of liver fibrosis.Ultrasonography202039328829710.14366/usg.1909032311869
     [Google Scholar]
  5. WellsP.N.T. LiangH.D. Medical ultrasound: Imaging of soft tissue strain and elasticity.J. R. Soc. Interface20118641521154910.1098/rsif.2011.005421680780
     [Google Scholar]
  6. AlmutairiF.F. AbdeenR. AlyamiJ. SultanS.R. Effect of depth on ultrasound point shear wave elastography in an elasticity phantom.Appl. Sci.20221213629510.3390/app12136295
     [Google Scholar]
  7. SultanS.R. AlghamdiA. AbdeenR. AlmutairiF. Evaluation of ultrasound point shear wave elastography reliability in an elasticity phantom.Ultrasonography202241229129710.14366/usg.2111435316890
     [Google Scholar]
  8. BotaS. HerknerH. SporeaI. SalzlP. SirliR. NeghinaA.M. Peck-RadosavljevicM. Meta-analysis: ARFI elastography versus transient elastography for the evaluation of liver fibrosis.Liver Int.20133381138114710.1111/liv.1224023859217
     [Google Scholar]
  9. FerraioliG. TinelliC. LissandrinR. ZicchettiM. BernuzziS. SalvaneschiL. FiliceC. Ultrasound point shear wave elastography assessment of liver and spleen stiffness: Effect of training on repeatability of measurements.Eur. Radiol.20142461283128910.1007/s00330‑014‑3140‑y24643497
     [Google Scholar]
  10. BarrR.G. FerraioliG. PalmeriM.L. GoodmanZ.D. Garcia-TsaoG. RubinJ. GarraB. MyersR.P. WilsonS.R. RubensD. LevineD. Elastography assessment of liver fibrosis: Society of radiologists in ultrasound consensus conference statement.Radiology2015276384586110.1148/radiol.201515061926079489
     [Google Scholar]
  11. WangJ.H. Application of ultrasound liver elastography to the diagnosis and monitoring of liver disease.J. Med. Ultrasound20192711210.4103/JMU.JMU_108_1831031528
     [Google Scholar]
  12. MaruyamaH. YokosukaO. Ultrasonography for noninvasive assessment of portal hypertension.Gut Liver201711446447310.5009/gnl1607828267700
     [Google Scholar]
  13. KoçZ. OğuzkurtL. UlusanS. Portal vein variations: Clinical implications and frequencies in routine abdominal multidetector CT.Diagn. Interv. Radiol.2007132758017562511
     [Google Scholar]
  14. BarrR.G. Shear wave liver elastography.Abdom. Radiol.201843480080710.1007/s00261‑017‑1375‑129116341
     [Google Scholar]
  15. ȘirliR. PopescuA. SporeaI. Liver fibrosis assessment by point shear-wave elastography techniques.Ultrasound Elastography.IntechOpen202010.5772/intechopen.87212
     [Google Scholar]
  16. LuntsiG. MuhammadM.A. ShiramaY.B. Lawal MohammedM. SuleimanA. OchieK. Sonographic evaluation of the portal vein diameter in patients with chronic liver disease in northeastern Nigeria.Ultrasound2021291364310.1177/1742271X2094498133552226
     [Google Scholar]
  17. OglatA. MatjafriM.Z. SuardiN. OqlatM. AbdelrahmanM. OqlatA. A review of medical doppler ultrasonography of blood flow in general and especially in common carotid artery.J. Med. Ultrasound201826131310.4103/JMU.JMU_11_1730065507
     [Google Scholar]
  18. SingalA.K. AhmadM. SolowayR.D. Duplex Doppler ultrasound examination of the portal venous system: An emerging novel technique for the estimation of portal vein pressure.Dig. Dis. Sci.20105551230124010.1007/s10620‑009‑0887‑019629688
     [Google Scholar]
  19. BochnakovaT. Hepatic venous pressure gradient.Clin. Liver Dis.202117314414810.1002/cld.103133868655
     [Google Scholar]
  20. FerraioliG. TinelliC. LissandrinR. ZicchettiM. Dal BelloB. FiliceG. FiliceC. Point shear wave elastography method for assessing liver stiffness.World J. Gastroenterol.201420164787479610.3748/wjg.v20.i16.478724782633
     [Google Scholar]
  21. BerzigottiA. PiscagliaF. Ultrasound in portal hypertension--part 2--and EFSUMB recommendations for the performance and reporting of ultrasound examinations in portal hypertension.Ultraschall Med.201233183222322479
     [Google Scholar]
  22. BaikS.K. Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension: A review.Liver Int.201030101403141310.1111/j.1478‑3231.2010.02326.x20731772
     [Google Scholar]
  23. LlopE. BerzigottiA. ReigM. EriceE. ReverterE. SeijoS. AbraldesJ.G. BruixJ. BoschJ. García-PaganJ.C. Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors.J. Hepatol.201256110310810.1016/j.jhep.2011.06.02721827733
     [Google Scholar]
  24. KitsonM.T. RobertsS.K. ColmanJ.C. PaulE. ButtonP. KempW. Liver stiffness and the prediction of clinically significant portal hypertension and portal hypertensive complications.Scand. J. Gastroenterol.201550446246910.3109/00365521.2014.96475825623641
     [Google Scholar]
  25. ChoiSY JeongWK KimY KimJ KimTY SohnJH Shear-wave elastography: A noninvasive tool for monitoring changing hepatic venous pressure gradients in patients with cirrhosis.Radiology201427339172610.1148/radiol.14140008
     [Google Scholar]
  26. VizzuttiF. ArenaU. RomanelliR.G. RegaL. FoschiM. ColagrandeS. PetrarcaA. MoscarellaS. BelliG. ZignegoA.L. MarraF. LaffiG. PinzaniM. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis.Hepatology20074551290129710.1002/hep.2166517464971
     [Google Scholar]
  27. LemoineM. KatsahianS. ZiolM. NahonP. Ganne-CarrieN. KazemiF. Grando-LemaireV. TrinchetJ.C. BeaugrandM. Liver stiffness measurement as a predictive tool of clinically significant portal hypertension in patients with compensated hepatitis C virus or alcohol-related cirrhosis.Aliment. Pharmacol. Ther.20082891102111010.1111/j.1365‑2036.2008.03825.x18691352
     [Google Scholar]
  28. ChinJ.L. ChanG. RyanJ.D. McCormickP.A. Spleen stiffness can non‐invasively assess resolution of portal hypertension after liver transplantation.Liver Int.201535251852310.1111/liv.1264725074281
     [Google Scholar]
  29. HanJ-Y. ChoJ.H. KwonH.J. NamK.J. Predicting portal hypertension as assessed by acoustic radiation force impulse: Correlations with the Doppler ultrasound.Br. J. Radiol.2012851016e404e40910.1259/bjr/7464892422815421
     [Google Scholar]
  30. ŞirliR. SporeaI. PopescuA. DănilăM. Ultrasound-based elastography for the diagnosis of portal hypertension in cirrhotics.World J. Gastroenterol.20152141115421155110.3748/wjg.v21.i41.1154226556985
     [Google Scholar]
  31. FangC. SidhuP.S. Ultrasound-based liver elastography: Current results and future perspectives.Abdom. Radiol.202045113463347210.1007/s00261‑020‑02717‑x32918106
     [Google Scholar]
/content/journals/cmir/10.2174/0115734056267877231026102925
Loading
Investigating the Correlation between Liver Ultrasound pSWE and Portal Vein Hemodynamics: Preliminary Findings
Curr. Med. Imaging 20, e15734056267877 (2024); https://doi.org/10.2174/0115734056267877231026102925
/content/journals/cmir/10.2174/0115734056267877231026102925
/content/journals/cmir/10.2174/0115734056267877231026102925
Loading

Data & Media loading...


  • Article Type:     Research Article
Keyword(s): Elastography; Hemodynamics; Liver stiffness; Portal vein; PSWE; Ultrasound

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test