Current Drug Therapy - Volume 17, Issue 3, 2022

Background: Dermatomycosis is a type of fungal infection that can infect human skin, hair, and nails; an increasing growth of fungal infections ranging from superficial to systemic infection is alarming. Common causative agents are Candida, Cryptococcus, Aspergillus, and Pneumocystis species. A wide range of antifungal drugs is used for the treatment of mycotic infections. These antifungal drugs can be oral or topical. Read More

Proteoglycans are essential biomacromolecules that participate in matrix structure and organization, cell proliferation and migration, and cell surface signal transduction. However, their roles in physiology, particularly in CNS, remain incompletely deciphered. Numerous studies highlight the elevated levels of chondroitin sulphate proteoglycans (CSPGs) in various diseases, like cancers, and neurological disorders, like spinal cor Read More

Background: Premedication is used prior to surgery to reduce the adverse effects that might result from general anesthesia. Objective: This study was performed to examine the types and utility of various pre-anesthetic agents in 100 patients aged between 3 and 60 years who were admitted to Baladrooz General Hospital for different surgical operations during February (winter) and April (spring) 2021. Methods: A total of 62 pa Read More

Background: Persistent hyperglycemia in diabetes mellitus (DM) is considered the leading cause of morbidity and mortality associated with both microvascular and macrovascular complications, having a greater economic impact. This study aimed to assess the impact of socioeconomic status, prescribing patterns, and patient compliance in type 2 diabetes mellitus patients. Methods: This study was carried out at the Dep Read More

Background: Fertility control becomes necessary for under-developed and developing nations for the betterment of the economy, environment, and society. Plant Plumeria acuminata, “Temple tree or Frangipani,” of the Apocynaceae family, has exhibited several activities similar to contraceptive medicine and is widely distributed in India. Objective: Present investigation aimed to study the anti-ovulatory and anti-impl Read More

Introduction: Zanthoxylum rhetsa fruits, a common spice in many cuisines, have proven to have a good therapeutic potential and are routinely used in food, medicine, and commerce. The present study was conducted to screen the in vitro antileukemic and antimalarial activities of the methanolic extract of Z. rhetsa fruits and conduct mechanistic studies for antileukemic activity. Methods: Methanol extract was prepare Read More

Background: Diabetes mellitus is a metabolic disorder that has become a major health issue in the modern era due to long-term health consequences. α-amylase and α-glucosidase are the key enzymes involved in the digestion of starchy foods, and the inhibition of these enzymes is regarded as a postprandial hyperglycemia control strategy. Objective: The primary goal of this work is to examine the antioxidant activit Read More