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- Volume 13, Issue 3, 2024
Current Biotechnology - Volume 13, Issue 3, 2024
Volume 13, Issue 3, 2024
- Biotechnology, Biochemistry & Molecular Biology, Applied Microbiology
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Recent Advances in Functions and Biotechnological Potential of Pleiotropic Transcriptional Factor AdpA
More LessThe specialized metabolism of the members of class Actinomycetes served as one of the deepest sources of compounds for the pharmaceutical industry. Within this class species of genus Streptomyces stand out as the most diverse and prolific producers of novel scaffolds. At some point at the end of the 20th century, chemical-microbiological screening of actinomycetes seemed to largely sa Read More
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Phytochemical Profiling and Molecular Investigation of Moringa Oleifera Lam. Leaves for Anti-Arthritic Potential: Assessment and Identification of Phytopharmaceuticals through GC-MS Analysis, In Silico Study, ADMET Analysis, and In Vitro Evaluation
Authors: Aanjaneya Mamgain, Rameshroo Kenwat and Rishi PaliwalBackground The drumstick tree, Moringa oleifera Lam. (family Moringaceae), is known as a magical plant due to its broad pharmacological activities. Traditionally, the leaves of this plant are used for anti-inflammatory action. However, the compounds in Moringa oleifera leaves and their mechanism that show anti-arthritic potential are unknown. Methods In this study, a preliminary phytochemical investigation of Moringa o Read More
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Zinc Gluconate Supplementation Protects against Methotrexate-induced Neurotoxicity in Rats via Downregulation of Oxidative Stress, Inflammation and Neuron-specific Enolase Reactivity in Rats
More LessBackground The global increase in the incidence of cancers, as well as neurotoxicity induced by cancer therapy, has necessitated research into agents that are neuroprotective without impeding cancer treatment. Objective The objective of this study is to investigate the neuroprotective effects of feed-added zinc on methotrexate-induced changes in rats. Methods Animals were grouped into normal control and methotrex Read More
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Isolation and Identification of Iron, Chromium, and Manganese Tolerant Filamentous Fungi from Mining Soil
Background In this study, filamentous fungi from iron mining soils in the Amazon were isolated and identified as Talaromyces verruculosus, Trichoderma pseudoasperelloides, Penicillium rolfsii, Aspergillus cf. pseudoviridinutans, Aspergillus niger, Purpureocillium lilacinum, and Penicillium cf. guaibinense. Objective The objective of this study was to evaluate the isolated strains for radial growth rate (VCR) on solid media and Read More
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Development of Quality Standard and a Comprehensive Quality Control Study of Bharngyadi Kvatha Churna: An Ayurvedic Formulation
Background Bharngyadi Kvatha Churna (BKC) is an important polyherbal formulation mentioned in the Ayurvedic Formulary of India (AFI) for the treatment of intermittent fever and chronic fever but lacks the presence of standardised quality control parameters. Aims The aim of the present study was to develop a quality standard of BKC and to carry out a comprehensive quality control study, including the evaluation of physi Read More
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